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Mc-Val-Cit-PABC-PNP

Cat. No. M5070

All AbMole products are for research use only, cannot be used for human consumption.

Mc-Val-Cit-PABC-PNP Structure
Synonym:

Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate

Size Price Availability Quantity
10mg USD 35  USD35 In stock
50mg USD 50  USD50 In stock
100mg USD 65  USD65 In stock
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Biological Activity

Mc-Val-Cit-PABC-PNP is a histone-cleavable peptide linker for antibody-drug couplings (ADCs) that can be used for the synthesis of ADCs such as Brentuximab vedotin.

Chemical Information
Molecular Weight 737.76
Formula C35H43N7O11
CAS Number 159857-81-5
Solubility (25°C) DMSO > 42 mg/ml
Storage 2-8°C, protect from light, sealed
References

[1] Zixuan Ye, et al. EGFR Targeted Cetuximab-Valine-Citrulline (vc)-Doxorubicin Immunoconjugates- Loaded Bovine Serum Albumin (BSA) Nanoparticles for Colorectal Tumor Therapy

[2] Qinhuai Lai, et al. Cryptophycin-55/52 based antibody-drug conjugates: Synthesis, efficacy, and mode of action studies

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  Catalog
Abmole Inhibitor Catalog




Keywords: Mc-Val-Cit-PABC-PNP, Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate supplier, Drug-Linker Conjugates for ADC, inhibitors, activators

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