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Iladatuzumab vedotin

Cat. No. M24847

All AbMole products are for research use only, cannot be used for human consumption.

Iladatuzumab vedotin Structure
Synonym:

DCDS-0780A

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Quality Control & Documentation
Biological Activity

Iladatuzumab vedotin (DCDS-0780A) is an antibody–drug conjugate (ADC) containing humanized IgG1 anti-human CD79B monoclonal antibody conjugated to MMAE via a protease labile linker. Iladatuzumab vedotin uses novel THIOMAB technology (TDC) to consistently conjugate two MMAE molecules per antibody using engineered cysteine residues. Iladatuzumab vedotin has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research.

Chemical Information
CAS Number 1906205-77-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Anthony Markham. Drugs. Tisotumab Vedotin: First Approval

[2] Emma D Deeks. Drugs. Disitamab Vedotin: First Approval

[3] Emma D Deeks. Drugs. Polatuzumab Vedotin: First Global Approval

[4] Carrie Van Der Weyden, et al. Expert Rev Hematol. Brentuximab vedotin in T-cell lymphoma

[5] Craig H Moskowitz, et al. Lancet. Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial

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Lys-SMCC-DM1

Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization.

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Mal-PEG4-VC-PAB-DMEA-PNU-159682 

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  Catalog
Abmole Inhibitor Catalog




Keywords: Iladatuzumab vedotin, DCDS-0780A supplier, Drug-Linker Conjugates for ADC, inhibitors, activators

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