|M10317||LNP023 hydrochloride (Iptacopan HCl)||Iptacopan (LNP023) hydrochloride is a first-in-class orally bioavailable, highly potent and selective complement factor B inhibitor with an IC50 value of 10 nM.|
|M10145||Danicopan (ALXN2040)||Danicopan (ALXN2040; ACH-4471; ACH-0144471) is a highly potent, orally active Factor D inhibitor.|
|M10140||TLQP-21 TFA||TLQP-21 is a VGF-derived peptide, which protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis and increases energy expenditure and prevents early phase diet-induced diabetes.|
|M10114||PMX 205 Trifluoroacetate||PMX 205 Trifluoroacetate is a potent complement antagonist of C5a (C5aR; CD88) receptor.|
|M9199||Avacopan||Avacopan (CCX168) is a potent, selective and orally available complement 5a receptor inhibitor with an IC50 of 0.1 nM.|
|M8983||Compstatin||Compstatinis is a 13-residue cyclic peptide, binds to complement component C3 and inhibits complement activation with IC50 of 12 μM.|
|M1598||Eculizumab||Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5.|
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