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JR14a is a potent thiophene antagonist of human complement C3a receptor. JR14a shows selectivity for the human C3a receptor over C5a receptor. JR14a can suppress C3aR-mediated inflammation.
| Molecular Weight | 533.47 |
| Formula | C25H26Cl2N4O3S |
| CAS Number | 2411440-41-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Complement System Products |
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| C5aR-IN-1
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| Empasiprubart
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