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Vilobelimab

Cat. No. M25043

All AbMole products are for research use only, cannot be used for human consumption.

Vilobelimab Structure
Synonym:

CaCP-29, IFX-1

Size Price Availability Quantity
100ug USD 170  USD170 In stock
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Quality Control & Documentation
Biological Activity

Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc.

Chemical Information
CAS Number 2250440-41-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Matthew W McCarthy. Expert Opin Biol Ther. Optimizing the use of vilobelimab for the treatment of COVID-19

[2] No authors listed. Vilobelimab

[3] Alexander P J Vlaar, et al. Lancet Respir Med. Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial

[4] Haruki Koike, et al. Neurol Ther. ANCA-Associated Vasculitic Neuropathies: A Review

[5] Alexander P J Vlaar, et al. Clin Transl Sci. The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19

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Keywords: Vilobelimab, CaCP-29, IFX-1 supplier, Complement System, inhibitors, activators

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