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Carbonic Anhydrase Carbonic Anhydrase

Cat.No.  Name Information
M8866 Zonisamide sodium salt Zonisamide sodium salt is an antiepileptic compound.
M5591 Dorzolamide HCl Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.
M3856 Acetazolamide Acetazolamide is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM.
M3421 Dichlorphenamide Dichlorphenamide is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.
M3305 Tioxolone Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.
M3099 U-104 U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 45.1 nM and 4.5 nM, respectively, very low inhibition for CA I and CA II.
M2843 Methyclothiazide Methyclothiazide is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including heart disease.
M2840 Methazolamide Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.
M2709 Fluorometholone Acetate Fluorometholone Acetate is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
M2690 Ethoxzolamide Ethoxzolamide is an inhibitor of the metalloenzyme carbonic anhydrase, which inhibits hCA I, hCA II, hCA IV, hCA VI and hCA VII with Ki of 25 nM, 8 nM, 93 nM, 43 nM and 0.8 nM, respectively.
M2444 Benzthiazide Benzthiazide is a thiazide diuretic, promoting water loss from the body.
M39054 hCAI/II-IN-6 hCAI/II-IN-6 is an orally active human carbonic anhydrase (CA) inhibitor. hCAI/II-IN-6 selectively inhibits hCA II and hCA VII isoforms with Ki values of 220, 4.9, 6.5 and >50000 nM for hCA I, hCA II , hCA VII and hCA XII respectively. hCAI/II-IN-6 shows anticonvulsant activity and anti maximal electroshock (MES) activity in vivo.
M30374 Sultiame Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic agent.
M30018 Fluorometholone acetate Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. Fluorometholone acetate potently inhibits carbonic anhydrase (CA) with IC50s of 2.18 μM and 17.5 μM for hCA-I and hCA-II, respectively. Fluorometholone acetate has anti-inflammatory effect and has the potential for external ocular inflammation research.
M29708 EMAC10101d  EMAC10101d is a potent and selective toward hCA II inhibitor, with a Ki of 8.1 nM.
M25289 Girentuximab Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC).
M20427 Benzenesulfonamide Benzenesulfonamide ia an inhibitor of carbonic anhydrases.

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