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Dorzolamide HCl is a water-soluble inhibitor of human carbonic anhydrase carbonic anhydrase II and IV with a Ki of 1.9 nM and 31 nM, respectively, and can be used in glaucoma-related studies.
| Molecular Weight | 360.9 |
| Formula | C10H16N2O4S3.HCl |
| CAS Number | 130693-82-2 |
| Form | Solid |
| Solubility (25°C) | 14 mg/mL in water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Carbonic Anhydrase Products |
|---|
| hCAIX-IN-5
hCAIX-IN-5 is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively. |
| Disulfamide
Disulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. |
| Quinethazone
Quinethazone is an orally active diuretic agent and is also a weak inhibitor of carbonic anhydrase. |
| Acetazolamide sodium
Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX.Acetazolamide reduces the production of intraocular aqueous humor and may be used in glaucoma-related studies. |
| WES-1
WES-1 is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM). |
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