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Girentuximab

Cat. No. M25289

All AbMole products are for research use only, cannot be used for human consumption.

Girentuximab Structure
Synonym:

G250; cG250

Size Price Availability Quantity
100ug USD 150  USD150 In stock
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Quality Control & Documentation
Biological Activity

Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC).

Chemical Information
CAS Number 916138-87-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Tim van Oostenbrugge, et al. Curr Opin Urol. Targeted PET/CT imaging for clear cell renal cell carcinoma with radiolabeled antibodies: recent developments using girentuximab

[2] Tais Basaco, et al. Pharmaceuticals (Basel). Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo

[3] Sumanta K Pal, et al. Nat Rev Urol. Kidney cancer: Finding a niche for girentuximab in metastatic renal cell carcinoma

Related Carbonic Anhydrase Products
hCAIX-IN-5 

hCAIX-IN-5 is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively.

Disulfamide 

Disulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM.

Quinethazone

Quinethazone is an orally active diuretic agent and is also a weak inhibitor of carbonic anhydrase.

Acetazolamide sodium

Acetazolamide sodium is a carbonic anhydrase (CA) IX inhibitor with an IC50 of 30 nM for hCA IX.Acetazolamide reduces the production of intraocular aqueous humor and may be used in glaucoma-related studies.

WES-1

WES-1 is an inhibitor of carbonic anhydrase IX (Ki: 55.9 μM).

  Catalog
Abmole Inhibitor Catalog




Keywords: Girentuximab, G250; cG250 supplier, Carbonic Anhydrase, inhibitors, activators

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