Free shipping on all orders over $ 500
Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M1881 | Tozasertib | Tozasertib (VX-680, MK-0457) is a potent and selective pan-Aurora kinase inhibitor active against all Bcr/Abl proteins. |
| M1752 | MLN8237 (Alisertib) | MLN8237 (Alisertib) is a second-generation, orally bioavailable, highly selective Aurora kinase A inhibitor with IC50 of 61 nM. |
| M1663 | AZD1152-HQPA | AZD1152-HQPA (Barasertib) is a highly potent and selective inhibitor of Aurora with Ki values of 0.36 and 1369 nM for Aurora B and Aurora A respectively. |
| M20733 | SP-96 | SP-146 is a potent, selective and non-ATP-competitive inhibitor of Aurora B with IC50 of 0.316 nM. SP-146 can be used for the research of triple negative breast cancer (TNBC). |
| M20284 | WAY-661516 | WAY-661516 is a Aurora kinase A inhibitor. |
| M20251 | WAY-638641 | WAY-638641 is a Aurora kinase A inhibitor. |
| M20247 | WAY-636982 | WAY-636982 is a Aurora kinase A inhibitor. |
| M20246 | WAY-636900 | WAY-636900 is a Aurora kinase A inhibitor. |
| M20245 | WAY-635767 | WAY-635767 is a Aurora kinase A inhibitor |
| M20244 | WAY-635764 | WAY-635764 is a Aurora kinase A inhibitor. |
| M20238 | WAY-634704 | WAY-634704 is a Aurora kinase A inhibitor. |
| M20235 | WAY-632963 | WAY-632963 is a Aurora kinase A inhibitor. |
| M20066 | WAY-298668 | WAY-298668 altering the lifespan of a eukaryotic organism |
| M13592 | ENMD-2076 Tartrate | ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively. |
| M13591 | Cenisertib | Cenisertib (AS-703569) is an ATP-competitive multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3. |
| M9895 | LY3295668 | LY3295668 (AK-01) is a potent, orally active and highly specific Aurora-A kinase inhibitor, with Ki values of 0.8 nM and 1038 nM for AurA and AurB, respectively. |
| M7537 | SNS-314 | SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively and less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. |
| M3931 | Aurora Kinase Inhibitor III | Aurora Kinase Inhibitor III is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM. |
| M3701 | SNS-314 Mesylate | SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. |
| M3555 | GSK1070916 | GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. |
| M3552 | PHA-680632 | PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3. |
| M3516 | MK-5108 | MK-5108 (VX-689) is a highly selective Aurora A inhibitor with IC50 of 0.064 nM and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. |
| M3221 | PF-03814735 | PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.
