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SP-96

Cat. No. M20733

All AbMole products are for research use only, cannot be used for human consumption.

SP-96 Structure

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Quality Control & Documentation
Biological Activity

SP-146 is a potent, selective and non-ATP-competitive inhibitor of Aurora B with IC50 of 0.316 nM. SP-146 can be used for the research of triple negative breast cancer (TNBC).

Chemical Information
Molecular Weight 453.47
Formula C25H20FN7O
Solubility (25°C) DMSO 91 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kay Geert A Hermann, et al. RMD Open. What amount of structural damage defines sacroiliitis: a CT study

[2] Naga Rajiv Lakkaniga, et al. Eur J Med Chem. Discovery of SP-96, the first non-ATP-competitive Aurora Kinase B inhibitor, for reduced myelosuppression

[3] David Jung, et al. J Cyst Fibros. Circulating CRP and calprotectin to diagnose CF pulmonary exacerbations

[4] K Schlegel, et al. Z Naturforsch C J Biosci. The pyoverdins of Pseudomonas sp. 96-312 and 96-318

[5] S Gupta, et al. J Commun Dis. Serodiagnosis of tuberculosis

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Derrone

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CD532 hydrochloride 

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Aurora kinase inhibitor-2 

Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B, respectively.

  Catalog
Abmole Inhibitor Catalog




Keywords: SP-96 supplier, Aurora Kinase, inhibitors, activators

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