| Cat.No. | Name | Information |
|---|---|---|
| M1997 | Oligomycin A | Oligomycin A is an inhibitor of mitochondrial ATP synthase and uncoupler of oxidative phosphorylation. |
| M7737 | Concanamycin A (Folimycin) | Concanamycin A (Folimycin) is a macrolide antibiotic and a specific vacuolar type H+-ATPase (V-ATPase) inhibitor. |
| M2294 | Brefeldin A | Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity. |
| M9587 | NDI-091143 | NDI-091143 is a novel potent inhibitor of human ATP-citrate lyase with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate. |
| M40568 | Apicularen B | Apicularen B is a cytotoxic macrolide produced by Archangium gephyra and is also a specific V-ATPase inhibitor. Its IC50 values range from 0.2 to 1.2 μg/mL and it exhibits weak activity against some Gram-positive bacteria. |
| M40567 | Apicularen A | Apicularen A is a macrolide isolated from the mucoid bacterium Chondrosporium spp. It is also a highly selective inhibitor of vesicular ATPase. |
| M39032 | Gitoxin | Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably. |
| M39031 | Marinobufogenin | Marinobufogenin is a strong inhibitor of Na+/K+ ATPase that has been identified in mammalian plasma. |
| M39030 | Stauntosaponin A | Stauntosaponin A, a steroid glycoside, is a potent inhibitor of Na(+)/K(+)-ATPase with an IC50 value of 21 nM. Stauntosaponin A can be isolated from Carnation and has potential anti-cancer research value. |
| M39019 | Oligomycin B | Oligomycin B is an antibiotic isolated from marine Streptomyces, used as an eukaryotic ATP synthase inhibitor, induces apoptosis. |
| M20735 | BRITE338733 | BRITE-338733 is a potent RecA (a DNA-dependent ATPase) inhibitor with IC50 of 4.7 µM. |
| M20711 | ML241 hydrochloride | ML241 hydrochloride is a potent and selective inhibitor of p97 with IC50 of 0.11 μM and 3.5 μM for p97 ATPase and UbG76V–GFP, respectively. |
| M19163 | Deslanoside | Deslanoside (Desacetyllanatoside C) inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations . |
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