| Cat.No. | Name | Information |
|---|---|---|
| M3669 | Micafungin Sodium | Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis, it is an antifungal agent. |
| M5868 | Penicillin G Sodium | Penicillin G Sodium is a β-lactam antibiotic produced by Penicillin spp. |
| M4947 | Streptomycin sulfate | Streptomycin sulfate is an antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis. |
| M4323 | Physcion | Physcion is an anthraquinone from roots of Rheum officinale Baill. |
| M2719 | G-418 disulfate | G-418 disulfate (Geneticin) blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. |
| M5415 | Amphotericin B | Amphotericin B (AmB) is an amphipathic polyene antibiotic which permeabilizes ergosterol-containing membranes. |
| M3594 | Neomycin sulfate | Neomycin sulfate belongs to a class of antibiotics known as the aminoglycosides. |
| M2391 | Ampicillin Trihydrate | Ampicillin Trihydrate is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. |
| M3311 | Metronidazole | Metronidazole is a nitroimidazole antibiotic that is used specifically for anaerobic bacteria and protozoa. |
| M4862 | Vancomycin HCl | Vancomycin HCl is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent. |
| M28100 | MUT056399 | MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli with 50% inhibitory concentration IC50s of 12 nM and 58 nM, respectively. |
| M27595 | Enmetazobactam | Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens. |
| M25574 | Durlobactam sodium | Durlobactam (ETX2514) sodium is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. |
| M25468 | Lipofermata | Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC50 of 4.84 μM in Caco-2 cells. |
| M25269 | Farletuzumab | Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a therapeutic humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer. |
| M22443 | Fluopyram | Fluopyram |
| M22437 | Eravacycline dihydrochloride | Eravacycline dihydrochloride |
| M22436 | Elubiol | Elubiol |
| M22426 | Cefamandole sodium | Cefamandole sodium |
| M22424 | Cyproconazole | Cyproconazole is a chiral triazole fungicide that exerts antimicrobial action by inhibiting the biosynthesis of ergostero. |
| M22416 | Bicyclomycin benzoate | Bicyclomycin benzoate |
| M22409 | Amikacin | Amikacin is a semi-synthetic kanamycin analog and an aminoglycoside antibiotic with antimicrobial activity against most Gram-negative bacteria, including gentamicin- and tobramycin-resistant strains. |
| M21967 | Cefepime | Cefepime is a semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
| M21928 | BTZ043 | BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively. |
| M21623 | Clavulanate Potassium | Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic. |
| M21508 | Ibezapolstat | Ibezapolstat (ACX-362E) is a first-of-its-kind (first-in-class) inhibitor of the orally active DNA polymerase IIIC (DNA pol IIIC) developed for use in the study of Clostridium difficile infection (CDI). |
| M21494 | Sibofimloc | Sibofimloc (CD-202) is a first-in-class, intestinal limiting and oral active inhibitor of FimH adhesion. Sibofimloc has antibacterial activity and is being developed for the study of inflammatory bowel disease (IBD). |
| M21490 | Omadacycline hydrochloride | Omadacycline (PTK 0796) hydrochloride, as a tetracycline antibiotic, is the first (first-in-class) orally active aminomethylcycline antimicrobial agent. Omadacycline hydrochloride is used to study acute bacterial skin and skin structure infections, infectious pneumonia, and urinary tract infections. |
| M21211 | Lalistat 1 | Lalistat 1 is a lysosomal acid lipase inhibitor with IC50 value of 68 nM. It can block LAL-mediated lipid hydrolysis of acetylated LDL and reduce efflux of cholesterol from lipid-loaded cells. |
| M20933 | Cefozopran hydrochloride | Cefozopran HCl is a fourth-generation cephalosporin. |
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