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Penicillin G Sodium

Cat. No. M5868
Penicillin G Sodium Structure
Synonym:

Benzylpenicillin Sodium

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
500mg USD 30  USD30 In stock
1g USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Penicillin G Sodium is a β-lactam antibiotic produced by Penicillin spp.

Product Citations
Chemical Information
Molecular Weight 356.37
Formula C16H18N2O4S.Na
CAS Number 69-57-8
Solubility (25°C) Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Nieto JE, et al. Can J Vet Res. Pharmacokinetics of a combination of amikacin sulfate and penicillin G sodium for intravenous regional limb perfusion in adult horses.

[2] Wenhui Ji, et al. FEMS Microbiol Lett. A novel endolysin disrupts Streptococcus suis with high efficiency

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