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Micafungin inhibits the synthesis of 1, 3-beta-D-glucan, an integral component of the fungal cell wall. Micafungin is a potential agent for disrupting the structure of a biofilm of P. aeruginosa allowing the possible exposure and treatment of core-planktonic cells. Micafungin (10 mg/mL) phenotypicly decreases the formation of biofilm in most of the isolates. For all the genes tested, the levels of mRNA transcription are also decreased significantly in micafungin-treated samples cf. their untreated counterparts.
Lett Appl Microbiol. 2019 Oct;69(4):271-278.
Synergistic effect of nikkomycin Z with caspofungin and micafungin against Candida albicans and Candida parapsilosis biofilms.
Micafungin Sodium purchased from AbMole
| Molecular Weight | 1292.26 |
| Formula | C56H70N9NaO23S |
| CAS Number | 208538-73-2 |
| Form | Solid |
| Solubility (25°C) | Water 100 mg/mL DMSO 30 mg/mL |
| Storage | 2-8°C, protect from light, sealed |
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