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Micafungin Sodium

Cat. No. M3669
Micafungin Sodium Structure

FK463 sodium

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 155  USD155 In stock
2mg USD 38  USD38 In stock
5mg USD 68  USD68 In stock
10mg USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Micafungin inhibits the synthesis of 1, 3-beta-D-glucan, an integral component of the fungal cell wall. Micafungin is a potential agent for disrupting the structure of a biofilm of P. aeruginosa allowing the possible exposure and treatment of core-planktonic cells. Micafungin (10 mg/mL) phenotypicly decreases the formation of biofilm in most of the isolates. For all the genes tested, the levels of mRNA transcription are also decreased significantly in micafungin-treated samples cf. their untreated counterparts.

Product Citations
Chemical Information
Molecular Weight 1292.26
Formula C56H70N9NaO23S
CAS Number 208538-73-2
Form Solid
Solubility (25°C) Water 100 mg/mL
DMSO 30 mg/mL
Storage 2-8°C, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Bazzi W, et al. Biofouling. The inhibitory effect of micafungin on biofilm formation by Pseudomonas aeruginosa.

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Keywords: Micafungin Sodium, FK463 sodium supplier, Antibiotic, inhibitors, activators

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