Free shipping on all orders over $ 500

Micafungin Sodium

Cat. No. M3669
Micafungin Sodium Structure
Synonym:

FK463 sodium

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 155  USD155 In stock
2mg USD 38  USD38 In stock
5mg USD 68  USD68 In stock
10mg USD 120  USD120 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Micafungin inhibits the synthesis of 1, 3-beta-D-glucan, an integral component of the fungal cell wall. Micafungin is a potential agent for disrupting the structure of a biofilm of P. aeruginosa allowing the possible exposure and treatment of core-planktonic cells. Micafungin (10 mg/mL) phenotypicly decreases the formation of biofilm in most of the isolates. For all the genes tested, the levels of mRNA transcription are also decreased significantly in micafungin-treated samples cf. their untreated counterparts.

Product Citations
Chemical Information
Molecular Weight 1292.26
Formula C56H70N9NaO23S
CAS Number 208538-73-2
Form Solid
Solubility (25°C) Water 100 mg/mL
DMSO 30 mg/mL
Storage 2-8°C, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Bazzi W, et al. Biofouling. The inhibitory effect of micafungin on biofilm formation by Pseudomonas aeruginosa.

Related Antibiotic Products
Quinupristin

Quinupristin is a streptogramin antibiotic.

Buforin II

Buforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide.

P-113

P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5.

CSP1

CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM.

Temporin A

Temporin A is a short alpha-helical antimicrobial peptide isolated from the skin of the frog Rana temporaria.

  Catalog
Abmole Inhibitor Catalog




Keywords: Micafungin Sodium, FK463 sodium supplier, Antibiotic, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.