Pancreatic cancer organoids recapitulate disease and allow personalized drug screening. 【IF: 12.779】Proc Natl Acad Sci U S A. 2019 Dec 9 Y-27632 dihydrochloride purchased from AbMole
DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation. 【IF: 12.779】Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22609-22618 Talazoparib purchased from AbMole
An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma. 【IF: 10.624】EMBO Mol Med. 2019 Aug;11(8):e9830 LY2157299 (Galunisertib) purchased from AbMole
Prominin-1 controls stem cell activation by orchestrating ciliary dynamics. 【IF: 10.557】EMBO J. 2019 Jan 15;38(2) Niltubacin purchased from AbMole
The Ewing Family of Tumors Relies on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity. 【IF: 10.199】Clin Cancer Res. 2019 Mar 1;25(5):1664-1675 AZD2281 (Olaparib) purchased from AbMole
NOTCH1 Represses MCL-1 Levels in GSI-resistant T-ALL, Making them Susceptible to ABT-263 【IF: 10.107】Clin Cancer Res. 2019 Jan 1;25(1):312-324 ABT-263 purchased from AbMole
Pre-existing Functional Heterogeneity of Tumorigenic Compartment as the Origin of Chemoresistance in Pancreatic Tumors. 【IF: 9.995】Cell Rep. 2019 Feb 5;1518-1532.e9 BEZ235 purchased from AbMole
SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα. 【IF: 9.995】Cell Rep. 2019 Dec 17;29(12):4127-4143.e8 WY 14643 (Pirinixic Acid) purchased from AbMole
Loss of transglutaminase 2 sensitizes for diet-induced obesity-related inflammation and insulin resistance due to enhanced macrophage c-Src signaling. 【IF: 9.685】Cell Death Dis. 2019 Jun 5;10(6):439 GW3965 hydrochloride purchased from AbMole
IL-12 Expands and Differentiates Human Vγ2Vδ2 T Effector Cells Producing Antimicrobial Cytokines and Inhibiting Intracellular Mycobacterial Growth. 【IF: 8.786】Front Immunol. 2019 Apr 26;10:913 Adezmapimod (SB203580) purchased from AbMole
Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation 【IF: 8.312】JCI Insight. 2019 Jul 23;5(16):e128336 Vatalanib dihydrochloride purchased from AbMole
Peperomin E and its orally bioavailable analog induce oxidative stress-mediated apoptosis of acute myeloid leukemia progenitor cells by targeting thioredoxin reductase. 【IF: 7.793】Redox Biol. 2019 Jun;24:101153 Cytarabine purchased from AbMole
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