Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy. 【IF: 38.272】Cancer Discov. 2019 Jul;9(7):852-871 Y-27632 dihydrochloride purchased from AbMole
A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth. 【IF: 25.269】Cell Stem Cell. 2019 Apr 4;24(4):654-669.e6 Tofacitinib purchased from AbMole
Gadofullerene Nanoparticles Reverse Dysfunctions of Pancreas and Improve Hepatic Insulin Resistance for Type 2 Diabetes Mellitus Treatment. 【IF: 18.027】ACS Nano. 2019 Aug 27;13(8):8597-8608 MK-2206 2HCl purchased from AbMole
Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence. 【IF: 17.694】Nat Commun. 2019 Jun 11;10(1):2556 Niraparib (MK-4827) purchased from AbMole
Rebalancing of actomyosin contractility enables mammary tumor formation upon loss of E-cadherin. 【IF: 17.694】Nat Commun. 2019 Aug 23;10(1):3800 Y-27632 dihydrochloride purchased from AbMole
Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells. 【IF: 17.694】Nat Commun. 2019 Dec 20;10(1):5799 Imatinib purchased from AbMole
DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation. 【IF: 12.779】Proc Natl Acad Sci U S A. 2019 Nov 5;116(45):22609-22618 Talazoparib purchased from AbMole
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening. 【IF: 12.779】Proc Natl Acad Sci U S A. 2019 Dec 9 Y-27632 dihydrochloride purchased from AbMole
An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma. 【IF: 10.624】EMBO Mol Med. 2019 Aug;11(8):e9830 LY2157299 (Galunisertib) purchased from AbMole
Prominin-1 controls stem cell activation by orchestrating ciliary dynamics. 【IF: 10.557】EMBO J. 2019 Jan 15;38(2) Niltubacin purchased from AbMole
The Ewing Family of Tumors Relies on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity. 【IF: 10.199】Clin Cancer Res. 2019 Mar 1;25(5):1664-1675 AZD2281 (Olaparib) purchased from AbMole
NOTCH1 Represses MCL-1 Levels in GSI-resistant T-ALL, Making them Susceptible to ABT-263 【IF: 10.107】Clin Cancer Res. 2019 Jan 1;25(1):312-324 ABT-263 purchased from AbMole
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