About 13 results found for searched term "p97" (0.236 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9035 | WHI-P97 | JAK |
| WHI-P97 is a JAK3 inhibitor with an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. | ||
| M2561 | NMS-873 | p97 |
| NMS-873 is an allosteric and specific p97 inhibitor with IC50 of 30 nM. | ||
| M2614 | DBeQ | p97 |
| JRF 12 | ||
| DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM. | ||
| M2862 | MNS | Src-bcr-Abl |
| NSC 170724; 5-(2-Nitrovinyl)benzodioxole | ||
| MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively. | ||
| M6700 | Eeyarestatin I | Others |
| Eeyarestatin-I | ||
| Eeyarestatin I is a potent endoplasmic reticulum-associated protein degradation (ERAD) and translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. | ||
| M6973 | ML 240 | Others |
| ML 240 is a aTP-competitive inhibitor of p97 ATPase. | ||
| M8610 | UPCDC30245 | Others |
| UPCDC30245 is an allosteric inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). | ||
| M13704 | CB-5083 | p97 |
| CB-5083 is a first-in-class, potent and selective, orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM. | ||
| M15078 | Recombinant Mouse Noggin/NOG (Mammalian,C-6His) | Recombinant Proteins |
| Noggin; Nog | ||
| Recombinant mouse Noggin was produced by the mammalian expression system, and the target gene encoding GLN28-CYS232 was expressed as 6His at the C-terminal. Accession # : P97466. | ||
| M19981 | Recombinant Rat MIP-3 α/CCL20 (HEK 293) | Recombinant Proteins |
| CCL-20; CKb4; Exodus; LARC; MIP-3-alpha | ||
| Macrophage inflammatory protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine in the CC chemokine family. Accession P97884 - # 1. | ||
| M20711 | ML241 hydrochloride | ATPase |
| ML241 hydrochloride is a potent and selective inhibitor of p97 with IC50 of 0.11 μM and 3.5 μM for p97 ATPase and UbG76V–GFP, respectively. | ||
| M28966 | CB-5339 | p97 |
| CB-5339 is a potent p97 inhibitor with an IC50 <30 nM (WO2015109285A1, compound FF07). | ||
| M30506 | NPD8733 | Others |
| NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 specifically binds to valosin-containing protein (VCP)/p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family. NPD8733 has the potential for the research of cancer diseases. | ||
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