About 13 results found for searched term "p97" (0.134 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9035 | WHI-P97 | JAK |
| WHI-P97 is a JAK3 inhibitor with an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. | ||
| M2561 | NMS-873 | p97 |
| NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with an IC50 value of 30 nM. | ||
| M2614 | DBeQ | p97 |
| JRF 12 | ||
| DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM. | ||
| M2862 | MNS | Src-bcr-Abl |
| NSC 170724; 5-(2-Nitrovinyl)benzodioxole | ||
| MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively. | ||
| M6700 | Eeyarestatin I | Others |
| Eeyarestatin-I | ||
| Eeyarestatin I is a potent endoplasmic reticulum-associated protein degradation (ERAD) and translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. | ||
| M6973 | ML 240 | Others |
| ML 240 is a aTP-competitive inhibitor of p97 ATPase. | ||
| M8610 | UPCDC30245 | Others |
| UPCDC30245 is an allosteric inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). | ||
| M13704 | CB-5083 | p97 |
| CB-5083 is a first-in-class, potent and selective, orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM. | ||
| M15078 | Recombinant Mouse Noggin/NOG (HEK293,C-6His) | Cytokines and Growth Factors |
| Noggin; Nog | ||
| Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin binds some BMPs such as BMP4 with high affinity and others such as BMP7 with lower affinity. It antagonizes BMP bioactivities by blocking epitopes on BMPs that are needed for binding to both type I and type II receptors. Accession # : P97466. | ||
| M19981 | Recombinant Rat MIP-3 α/CCL20 (HEK 293) | Cytokines and Growth Factors |
| CCL-20; CKb4; Exodus; LARC; MIP-3-alpha | ||
| Macrophage inflammatory protein-3 (MIP-3α), also known as chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC), is a small cytokine in the CC chemokine family. Accession P97884 - # 1. | ||
| M20711 | ML241 hydrochloride | ATPase |
| ML241 hydrochloride is a potent and selective inhibitor of p97 with IC50 of 0.11 μM and 3.5 μM for p97 ATPase and UbG76V–GFP, respectively. | ||
| M28966 | CB-5339 | p97 |
| CB-5339 is a potent p97 inhibitor with an IC50 <30 nM (WO2015109285A1, compound FF07). | ||
| M30506 | NPD8733 | Others |
| NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 specifically binds to valosin-containing protein (VCP)/p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family. NPD8733 has the potential for the research of cancer diseases. | ||
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