About 4 results found for searched term "WHI-P97" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9035 | WHI-P97 | JAK |
| WHI-P97 is a JAK3 inhibitor with an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. | ||
| M2891 | NSC 319726 | Cuproptosis |
| NSC-319726; ZMC1 | ||
| NSC 319726 is a p53(R175) mutant activator that inhibits the growth of p53(R175) mutant cells and acts on p53(R175) mutant cells with IC50 of 8 nM, which has no inhibition on p53 wild-type cells. NSC 319726 is a potent copper ion-carrier that can be used in cuproptosis studies. | ||
| M21391 | Praliciguat | Guanylate Cyclase |
| IW-1973 | ||
| Praliciguat (IW-1973) is a potent, orally available promoter of soluble guanylate cyclase, which enhances the NO signaling pathway and is a vasodilator. In HEK-293 cells, Praliciguat (IW-1973) was able to stimulate sGC with an EC50 value of 197 nM. | ||
| M58704 | 4-methylumbelliferyl α-D-glucopyranoside | Fluorescent Dye |
| 4-MU-α-D-Glucopyranoside; 4-Methylumbelliferyl-α-D-Glucose | ||
| 4-Methylumbelliferyl-α-D-Glucopyranoside is a fluorescent substrate for α-glucosidase (GAA), which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU has pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), respectively. | ||
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