About 11 results found for searched term "USP7-IN-1" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13632 | USP7-IN-1 | Deubiquitinase |
| USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. | ||
| M41451 | USP7-IN-12 | Deubiquitinase |
| USP7-IN-12 is a potent and orally active Usp7 inhibitor with an IC50 value of 3.67 nM. | ||
| M10751 | USP7-IN-8 | Deubiquitinase |
| USP7-IN-8 is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM in the Ub-Rho110 assay.USP7-IN-8 is inactive against USP47 and USP5.USP7-IN-8 has anticancer effects. | ||
| M20691 | USP25/28 inhibitor AZ1 | Others |
| AZ1 is a potent and noncompetitive dual Inhibitors of the ubiquitin-specific protease (USP) 25/28 with IC50s of 0.62 μM and 0.7 μM in Ub-RH110 assay,respectively. | ||
| M21519 | U7D-1 | PROTAC |
| U7D-1 is a first-in-class, potent and selective ubiquitin-specific protease 7 USP7 PROTAC depressant in RS4; The DC50 in 11 cells was 33 nM. U7D-1 has anti-cancer activity. | ||
| M24850 | Bintrafusp alfa | TGF-beta/Smad |
| M 7824; MSB0011359C | ||
| Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer. | ||
| M24993 | Cinrebafusp alfa | EGFR/HER2 |
| PRS 343 | ||
| Cinrebafusp alfa (PRS 343) is a high affinity CD137/HER2 bispecfic anticalin-based drug. Cinrebafusp alfa binds to recombinant human HER2 (Kd=0.3 nM) and human monomeric CD137 (4-1BB; Kd=5 nM). Cinrebafusp alfa facilitates T-cell costimulation by tumor-localized, HER2-dependent 4-1BB clustering and activation, further enhancing T-cell receptor-mediated activity and leading to tumor destruction. Cinrebafusp alfa has the potential for HER2+ solid tumors research. | ||
| M27876 | LCAHA | Deubiquitinase |
| LCA hydroxyamide | ||
| LCAHA (LCA hydroxyamide) is a deubiquitinase USP2a inhibitor with IC50s of 9.7 μM and 3.7μM in Ub-AMC Assay and Di-Ub Assay, respectively. LCAHA destabilizes Cyclin D1 and induces G0/G1 arrest by inhibiting deubiquitinase USP2a. | ||
| M28037 | USP7/USP47 inhibitor | Deubiquitinase |
| USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively. | ||
| M40134 | 7-Xylosyl-10-Deacetyltaxol C | Others |
| 7-Xylosyl-10-Deacetyltaxol C (7-Xylosyl-10-Deacetylpaclitaxel C) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol C has anti-tumor activity and inhibits the growth of S180 sarcoma. | ||
| M40201 | 7-Xylosyl-10-Deacetyltaxol B | Others |
| 7-Xylosyl-10-Deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative derived from T. cuspidate. 7-Xylosyl-10-Deacetyltaxol B has anti-tumor activity and inhibits the growth of S180 sarcoma. | ||
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