About 12 results found for searched term "TB5" (0.051 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2029 | Sitaxsentan sodium | Endothelin Receptor |
| TBC-11251 | ||
| Sitaxsentan (TBC-11251) is an orally active, highly selective antagonist of endothelin A receptors. | ||
| M2474 | BTB06584 | ATPase |
| BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. | ||
| M5817 | Nitisinone | Others |
| NTBC; Nitisone; SC0735 | ||
| Nitisinone (SC0735) is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. | ||
| M8791 | TB5 | Others |
| TB5 is a potent and selective reversible inhibitor of monoamine oxidase B (MAOB) with a Ki value of 110 nM. | ||
| M9444 | Cenicriviroc Mesylate | CCR |
| TBR-652 Mesylate; TAK-652 Mesylate | ||
| Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, and it also inhibits both HIV-1 and HIV-2. | ||
| M9546 | TBK1/IKKε-IN-5 | IκB/IKK |
| ABM-7653; TBK1/IKK-epsilon-IN-5 | ||
| TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively. | ||
| M10190 | Cenicriviroc | CCR |
| TAK-652; TBR-652 | ||
| Cenicriviroc, also known as TAK-652 and TBR-652, is an orally active, dual antagonist of CCR2/CCR5. | ||
| M28070 | TBA-354 | Antibiotic |
| TBA-354 is a potent anti-tuberculosis compound. TBA-354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates. TBA-354 is 5 to 10 times more potent than PA-824, but selected mutants are cross-resistant to PA-824 and delamanid. | ||
| M28942 | Sitaxsentan | Endothelin Receptor |
| IPI 1040; TBC-11251 | ||
| Sitaxsentan (IPI 1040; TBC-11251) is a selective endothelin A (ETA) receptor antagonist. Antihypertensive. Sitaxsentan is used in treatment of chronic heart failure. IC50 value: Target: ETA receptor | ||
| M29445 | TBAJ-587 | Antibiotic |
| TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively. TBAJ-587 inhibits hERG channel minimally, attenuates inhibition of the cardiac potassium channel protein coded by the hERG, which is important for cardiac repolarization. | ||
| M30811 | TB500 | Peptides |
| TB500 is a synthetic version of an active region of thymosin β4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation. | ||
| M41082 | Mtb-IN-5 | Antibiotic |
| Mtb-IN-5 is an isoxazole, with anti-Mycobacterium tuberculosis (Mtb) activity. | ||
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