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Sitaxsentan

Cat. No. M28942

All AbMole products are for research use only, cannot be used for human consumption.

Sitaxsentan Structure
Synonym:

IPI 1040; TBC-11251

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Quality Control & Documentation
Biological Activity

Sitaxsentan (IPI 1040; TBC-11251) is a selective endothelin A (ETA) receptor antagonist. Antihypertensive. Sitaxsentan is used in treatment of chronic heart failure. IC50 value: Target: ETA receptor

Chemical Information
Molecular Weight 454.9
Formula C18H15ClN2O6S2
CAS Number 184036-34-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Iain M MacIntyre, et al. Drugs Today (Barc). Sitaxsentan sodium for pulmonary hypertension

[2] Neal J Benedict. Am J Health Syst Pharm. Sitaxsentan in the management of pulmonary arterial hypertension

[3] Eric T Wittbrodt, et al. Ann Pharmacother. Sitaxsentan for treatment of pulmonary hypertension

[4] Robyn J Barst. Expert Opin Pharmacother. Sitaxsentan: a selective endothelin-A receptor antagonist, for the treatment of pulmonary arterial hypertension

[5] Allison C Widlitz, et al. Expert Rev Cardiovasc Ther. Sitaxsentan: a novel endothelin-A receptor antagonist for pulmonary arterial hypertension

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Keywords: Sitaxsentan, IPI 1040; TBC-11251 supplier, Endothelin Receptor, inhibitors, activators

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