About 9 results found for searched term "Sphingosine" (0.174 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7319 | Sphingosine-1-phosphate | S1P Receptor |
| S1P | ||
| Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. | ||
| M10027 | C2 Ceramide | Phosphatase |
| N-Acetyl-D-sphingosine | ||
| C2 Ceramide (N-Acetyl-D-sphingosine) is a cell-permeable and biologically active ceramide, it induces differentiation and apoptosis in cells and has been shown to activate protein phosphatases. | ||
| M20681 | Sphingosine | Metabolite/Endogenous Metabolite |
| D-erythro-Sphingosine; erythro-C18-Sphingosine | ||
| Sphingosine (D-erythro-Sphingosine, Erythrosphingosine) is an 18-carbon amino alcohol with an unsaturated hydrocarbon chain, which forms a primary part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid. | ||
| M27913 | N,N-Dimethylsphingosine | SPHK |
| N,N-Dimethylsphingosine is a potent inhbitor of SphK (sphingosine kinase) as an endogenous metabolite of sphingosine produced in various tissues and tumor cell lines. | ||
| M30232 | Glucosylsphingosine | Others |
| Glucopsychosine; Lyso-Gb1 | ||
| Glucosylsphingosine (lyso-Gb1) is a deacylated form of glucosylceramide and is also degraded by the glucocerebrosidase. Glucosylsphingosine is a very promising, reliable and specific biomarker for monitoring Gaucher disease. | ||
| M30569 | C8-Ceramide | Apoptosis |
| N-Octanoyl-D-erythro-sphingosine | ||
| C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro. | ||
| M38823 | Phytosphingosine | Apoptosis |
| 4-Hydroxysphinganine | ||
| Phytosphingosine is a phospholipid and has anti-cancer activities. Phytosphingosine induces cell apoptosis via caspase 8 activation and Bax translocation in cancer cells. | ||
| M56967 | C12-Sphingosine | Others |
| C12-Sphingosine is a short-chain Sphingosine homologue. | ||
| M58417 | C6 Ceramide | Apoptosis |
| C6-Cer; N-Hexanoylsphingosine | ||
| C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. | ||
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