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 About 13 results found for searched term "Sirtuin" (0.137 seconds)

Cat.No.  Name Target
M4678 Fisetin Sirtuin
Fustel
Fisetin (Fustel) is a potent sirtuin activating compound (STAC) and an agent that modulates sirtuins.
M4896 Nicotinamide Sirtuin
Vitamin B3; Nicotinic acid amide; Niacinamide
Nicotinamide is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins. Nicotinamide plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions.
M7868 JFD00244 Others
JFD00244 is a SIRT (sirtuin, human silent information regulator) inhibitor.
M9876 UBCS039 Sirtuin
UBCS 039
UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM.
M10109 SRT2183 Sirtuin
SRT-2183
SRT2183 is a selective activator of Sirtuin-1 (SIRT1) with EC1.5 value of 0.36 μM.
M10970 SRT 1460 Sirtuin
SRT 1460 is a potent Sirtuin-1 (SIRT1) agonist EC1.5 The value is 2.9 μM.
M13734 MC3482 Sirtuin
MC3482 is a specific sirtuin5 (SIRT5) inhibitor.
M13735 SIRT5 inhibitor 1 Sirtuin
SIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM.
M20020 CL-59089 Sirtuin
CL-59089 is a sirtuin modulator.
M20212 WAY-616312 Sirtuin
WAY-616312 is a sirtuin modulator.
M27669 E1231 Sirtuin
1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one
E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 μM) and deacetylated liver X receptor-alpha (LXRα), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE-/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases.
M38950 Tanshindiol C Histone Methyltransferase
Tanshindiol C is a S-adenosylmethionine-competitive EZH2 (Histone Methyltransferase) inhibitor with an IC50 of 0.55 μM for inhibiting the methyltransferase activity. Tanshindiol C is also an activator of both Nrf2 and Sirtuin 1 (Sirt1) in macrophages.
M41604 Z26395438 Sirtuin
Z26395438 is a potent Sirtuin-1 inhibitor, with an IC50 value of 1.6 μM.



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