About 14 results found for searched term "SC79" (0.057 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1807 | SCH727965 (dinaciclib) | CDK |
| Dinaciclib | ||
| SCH727965 (Dinaciclib) is a potent and selective CDK inhibitor with IC50 values of 1, 1, 3 and 4 nM for CDK2, CDK5, CDK1 and CDK9, respectively. | ||
| M2358 | 3-Deazaneplanocin A | Histone Methyltransferase |
| NSC 617989; 3-Deazaneplanocin; DZNep | ||
| 3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM. | ||
| M2823 | Loxistatin Acid(E-64C) | Cathepsin |
| NSC 694279, EP 475 | ||
| Loxistatin Acid (E-64C), a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor. | ||
| M2892 | NSC697923 | E1/E2/E3 Enzyme |
| NSC697923 is a cell-permeable and selective inhibitor of the Ub-conjugating enzyme (E2) complex Ubc13-Uev1A. | ||
| M4607 | Phloretin | SGLT |
| NSC 407292; RJC 02792 | ||
| Phloretin (NSC 407292; RJC 02792) is a specific, competitive and orally active inhibitor of sodium/glucose cotransporters in the intestine (SGLT1) and kidney (SGLT2). | ||
| M5153 | SC79 | Akt |
| SC79 is a specific and BBB permeable Akt activator used to enhance Akt activity. SC79 activates Akt in the cytosol and inhibits Akt membrane translocation. SC79 specifically binds to the PH domain of Akt. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M5834 | Oltipraz | HIF |
| RP 35972; NSC 347901 | ||
| Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). | ||
| M5835 | Ondansetron Hydrochloride Dihydrate | 5-HT Receptor |
| GR 38032; SN 307; NSC 665799 | ||
| Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors. | ||
| M6336 | 3-Deazaneplanocin A hydrochloride | Histone Methyltransferase |
| DZNep hydrochloride; NSC 617989 hydrochloride; 3-Deazaneplanocin hydrochloride | ||
| 3-Deazaneplanocin A hydrochloride（DZNep HCl） is a eZH2 histone methyltransferase inhibitor. | ||
| M8706 | NSC57969 | Others |
| NSC57969 is a MDR-selective compound that exhibits a robust Pgp-dependent toxic activity across diverse cancer cell lines. | ||
| M9023 | Ellipticine | Topoisomerase |
| CCG36483; NSC71795 | ||
| Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. | ||
| M9695 | Ellipticine hydrochloride | Topoisomerase |
| NSC71795 hydrochloride | ||
| Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent which inhibits DNA topoisomerase II activities. | ||
| M14050 | SCH79797 | PAR |
| SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. | ||
| M14415 | Umbelliferone | Metabolite/Endogenous Metabolite |
| 7-Hydroxycoumarin; Hydrangin; NSC 19790 | ||
| Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. | ||
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