About 30 results found for searched term "Rutin" (0.021 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1825 | PCI-32765 | BTK |
| Ibrutinib; CRA-032765 | ||
| PCI-32765 (Ibrutinib) is a potent, selective and orally bioavailable irreversible inhibitor of BTK with IC50 value of 0.46 nM. | ||
| M2113 | Spebrutinib (AVL-292) | BTK |
| CC-292; Spebrutinib | ||
| Spebrutinib (AVL-292) is an oral, potent and selective small molecule covalent inhibitor of Btk (IC50 < 0.5 nM). | ||
| M3894 | Rutin | Amyloid |
| Rutoside; Quercetin 3-O-rutinoside | ||
| Rutin is a flavonol glycoside found in many plants including buckwheat, tobacco, forsythia, hydrangea, viola, etc., which possesses healthy effects for human. | ||
| M4235 | Kaempferol-3-O-rutinoside | Others |
| Nicotiflorin is a flavonoid glycoside extracted from Flos Carthami, a traditional Chinese medicine. Nicotiflorin has potent antiglycation activity and neuroprotective effect. | ||
| M4236 | Narcissoside | Others |
| Isorhamnetin-3-O-β-D-rutinoside | ||
| Narcissin (Narcissoside) is a coptidis glycoside that clears ONOO- and sin-1 derived ONOO- with IC50 of 3.5 and 9.6 μM, respectively. It has antioxidant activity. | ||
| M4400 | Narirutin | Antibiotic |
| Narirutin is one of the active ingredients isolated from Citrus unshiu and has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tuberculosis potency. | ||
| M5257 | ONO-4059 hydrochloride | BTK |
| GS-4059 hydrochloride; Tirabrutinib hydrochloride | ||
| ONO-4059 (GS-4059) hydrochloride is highly potent and selective BTK inhibitor with an IC50 of 2.2 nM. | ||
| M5306 | Acalabrutinib | BTK |
| ACP-196 | ||
| Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.BMX, and TEC, respectively) and no activity against EGFR. | ||
| M5333 | Tirabrutinib (ONO-4059) | BTK |
| Tirabrutinib; GS-4059; Velexbru | ||
| Tirabrutinib (ONO-4059) is a highly selective, orally bioavailable BTK inhibitor with a potency (IC50) of 2.2 nM. | ||
| M5689 | Hesperidin | Apoptosis |
| Hesperetin 7-rutinoside | ||
| Hesperidin (HP) is a bioflavonoid that plays a role in plant defense and is abundant in citrus species, such as grapefruit, lemon and orange. Hesperidin is used effectively as a supplemental agent in complementary therapy protocols. | ||
| M10604 | Pirtobrutinib (LOXO-305) | BTK |
| LY 3527727; RXC-005 | ||
| Pirtobrutinib (LOXO-305; LY 3527727; RXC-005) is a first-in-class, highly selective, non-covalent, next-generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells.Pirtobrutinib's selectivity for BTK more than 300 times more selective than other 370 kinases. Pirtobrutinib can be used in studies related to chronic lymphocytic leukemia (CLL). | ||
| M8583 | Ferutinin | Others |
| An ERα (estrogen receptor) agonist; phytoestrogen. | ||
| M8941 | GDC-0853 (Fenebrutinib) | BTK |
| Fenebrutinib; RG7845 | ||
| GDC-0853 (Fenebrutinib) is a potent, selective and non-covalent bruton tyrosine kinase (Btk) inhibitor with a Ki value of 0.91 nM against BRK. | ||
| M9628 | Branebrutinib | BTK |
| BMS-986195 | ||
| Branebrutinib (BMS-986195) is a potent, covalent, irreversible inhibitor of Bruton’s tyrosine kinase (BTK), with IC50 of 0.1 nM. | ||
| M9958 | ARQ 531 | BTK |
| ARQ-531；MK-1026; Nemtabrutinib | ||
| ARQ 531 is a potent reversible inhibitor of BTK (IC50 = 0.85 nM), exhibits potent antitumor activity in ibrutinib-resistant diffuse large B-cell lymphoma. | ||
| M10025 | Zanubrutinib | BTK |
| BGB-3111 | ||
| Zanubrutinib (BGB-3111) is a potent and highly selective small molecule inhibitor of Bruton's tyrosine kinase (BTK). | ||
| M10095 | Orelabrutinib | BTK |
| ICP-022 | ||
| Orelabrutinib is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK). | ||
| M10274 | Tolebrutinib | BTK |
| SAR442168; PRN2246 | ||
| Tolebrutinib (SAR442168) is a potent, selective, orally active and blood-brain barrier capable bruton's tyrosine kinase (BTK) inhibitor with IC50 values of 0.4 and 0.7 nM in Ramos B cells and HMC microglia, respectively. Tolebrutinib has an effect on central nervous system immunity. Tolebrutinib can be used in multiple sclerosis (MS) studies. | ||
| M10500 | Remibrutinib (LOU064) | BTK |
| LOU064 | ||
| Remibrutinib (LOU064) is a potentially best-in-class "best-in-class" orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM and an IC50 value of 0.23 μM for inhibition of BTK activity in blood. Remibrutinib can be used to study chronic urticaria (CU). | ||
| M10605 | Rilzabrutinib | BTK |
| PRN1008 | ||
| Rilzabrutinib, also known as PRN1008, is a reversible covalent, selective and oral active inhibitor of Bruton’s Tyrosine Kinase (BTK) with IC50 of 1.3 nM. | ||
| M10629 | Troxerutin | NLR |
| Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species (ROS) and depress ER stress-mediated NOD activation. | ||
| M10896 | Vecabrutinib | BTK |
| SNS-062 | ||
| Vecabrutinib (SNS-062) is a potent, non-covalent BTK and ITK inhibitor,Kd The values are 0.3 nM and 2.2 nM, respectively. Vecabrutinib for ITK IC50 The value is 24 nM. | ||
| M14555 | Rutin hydrate | Amyloid |
| Rutoside hydrate; Quercetin 3-O-rutinoside hydrate | ||
| Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. | ||
| M14879 | (±)-Zanubrutinib | BTK |
| (±)-BGB-3111 | ||
| (±)-Zanubrutinib ((±)-BGB-3111) is a potent, selective and orally available Bruton's tyrosine kinase (Btk) inhibitor. | ||
| M14882 | Ibrutinib-biotin | BTK |
| Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, extracted from patent WO2014059368A1 Compound 1-5, has an IC50 of 0.755-1.02 nM for BTK. | ||
| M16207 | Physcion 8-O-rutinoside | Anthraquinones |
| Physcion 8-O-rutinoside | ||
| M16560 | Kaempferol 3-O-(2''-O-glucosyl)rutinoside | Flavonoids |
| Kaempferol 3-O-(2''-O-glucosyl)rutinoside | ||
| M16681 | 2"-O-Glucosylrutin | Flavonoids |
| 2"-O-Glucosylrutin | ||
| M17409 | Eugenol rutinoside | Phenylpropanoids |
| Eugenol rutinoside | ||
| M17453 | Ethyl rutinoside | Saccharides |
| Ethyl rutinoside | ||
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