Rosiglitazone - Search Results

About 5 results found for searched term "Rosiglitazone" (0.131 seconds)

Cat.No.	Name	Target
M1894	Rosiglitazone	PPAR
	BRL 49653
	Rosiglitazone (BRL 49653) is an orally active selective PPARγ agonist (EC50=60 nM, Kd=40 nM). Rosiglitazone is an TRPC5 activator (EC50=30 μM) and TRPM3 inhibitor.
M2038	Rosiglitazone maleate	PPAR
	Avandia
	Rosiglitazone maleate (Avandia) is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM.
M5940	Rosiglitazone HCl	PPAR
	BRL-49653 HCl
	Rosiglitazone HCl is a hypoglycemic compound that stimulates insulin secretion by binding to PPAR receptors in fat cells.
M28026	DS-6930	PPAR
	DS-6930 is a potent and selective agonist of PPARγ, with an EC50 of 41 nM. DS-6930 could robust reduce plasma glucose (PG), and with fewer PPARγ-related adverse effects than Rosiglitazone. DS-6930 can be used for the research of diabetes.
M29897	AMG131	PPAR
	INT131
	AMG131 (INT131), a potent and highly selective PPARγ partial agonist, binds to PPARγ and displaces Rosiglitazone with a Ki of ~10 nM. AMG131 can be used for research of type-2 diabetes mellitus (T2DM).