About 8 results found for searched term "RV01" (0.062 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3000 | Intepirdine | 5-HT Receptor |
| GSK 742457; SB-742457; RVT-101 | ||
| Intepirdine (SB742457) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63, exhibits >100-fold selectivity over other receptors. | ||
| M6153 | E6005 | PDE |
| RVT-501 | ||
| RVT-501 (E6005) is a selective phosphodiesterase 4 (PDE4PDE4) inhibitor with an IC50 of 2.8 nM. | ||
| M9197 | Relugolix | LHRH/GnRH |
| Orgovyx; TAK-385; RVT-601 | ||
| Relugolix, also known as TAK-385, is an orally active gonadotropin-releasing hormone (GnRH) antagonist with an IC50 of 0.12 nM. | ||
| M24540 | Teprotumumab | IGF-1R |
| RV001; R1507 | ||
| Teprotumumab (RV001, R1507) is a first-in-class IGF-1 receptor (IGF-1R) blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research. | ||
| M25262 | Ordesekimab | IL Receptor/Related |
| AMG 714; PRV-015 | ||
| Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15 (Interleukin Related) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD). | ||
| M31093 | RV01 | ALDH |
| RV01 is a novel quinolyl-substituted analogue of resveratrol, it inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol. RV01 exhibits hydroxyl radical scavenging activity. | ||
| M42652 | TRV-7019 | AChR/AChE |
| TRV-7019 is a BBB-penetrable radioligand for brain imaging that target butyrylcholinesterase. | ||
| M49437 | Afimkibart | TNF Receptor |
| PF-06480605; RVT-3101 | ||
| Afimkibart (PF-06480605) is an IgG1 human monoclonal antibody against TNF-like ligand 1A (TL1A, TNFSF15), which can be used in studies related to ulcerative colitis (UC). | ||
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