About 15 results found for searched term "ROCK-IN-7" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7388 | TC-S 7001 | ROCK |
| ROCK inhibitor; TC-S 7001 | ||
| TC-S 7001 is a potent and highly selective ROCK inhibitor; orally active. | ||
| M41596 | ROCK-IN-7 | ROCK |
| ROCK-IN-7 is a ROCK kinase inhibitor. | ||
| M49539 | ROCK2-IN-7 | ROCK |
| ROCK2-IN-7 is a kinase inhibitor targeting to ROCK2. | ||
| M1817 | Y-27632 dihydrochloride | ROCK |
| Y27632; Y-27632 2HCl | ||
| Y-27632 is a potent, selective inhibitor of Rho-associated protein kinases (ROCK) with IC50 values of 140-220 nM for ROCK1 and ROCK2. In addition, Y-27632 inhibited LPA-induced entosis. | ||
| M5123 | Y-39983 dihydrochloride | ROCK |
| Y-33075 dihydrochloride | ||
| Y-39983 (Y-33075) dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM, derived from Y-27632, inhibited ROCK more potently than Y-27632. | ||
| M5260 | Hydroxyfasudil hydrochloride | ROCK |
| HA-1100 HCl | ||
| Hydroxyfasudil (HA-1100), an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively. | ||
| M13728 | Hydroxyfasudil | ROCK |
| HA-1100 | ||
| Hydroxyfasudil is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively. | ||
| M13730 | RKI-1447 dihydrochloride | ROCK |
| RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC50s of 14.5 and 6.2 nM for ROCK1 and ROCK2, respectively. RKI 1447 dihydrochloride suppresses colorectal carcinoma cell growth and promotes apoptosis. | ||
| M13731 | ROCK inhibitor-2 | ROCK |
| ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC50s of 17 nM and 2 nM, respectively. | ||
| M13733 | Y-33075 | ROCK |
| Y 39983 | ||
| Y-33075 is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM. | ||
| M28188 | Sovesudil | ROCK |
| PHP-201; AMA0076 | ||
| Sovesudil (PHP-201) is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil lowers intraocular pressure (IOP) without inducing hyperemia. | ||
| M31008 | Sovesudil hydrochloride | ROCK |
| PHP-201 hydrochloride; AMA0076 hydrochloride | ||
| Sovesudil (PHP-201) hydrochloride is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil hydrochloride lowers intraocular pressure (IOP) without inducing hyperemia. | ||
| M41592 | THK01 | ROCK |
| THK01 is a potent ROCK2 inhibitor with IC50 values of 5.7 and 923 nM for ROCK2 and ROCK1, respectively. | ||
| M49532 | GSK-25 | ROCK |
| GSK-25 is a potent, selective and orally bioavailable ROCK1 inhibitor (IC50=7 nM). | ||
| M49772 | Akt/ROCK-IN-1 | ROCK |
| Akt/ROCK-IN-1 (B12) is a dual inhibitor for Akt and ROCK, with the IC50s of 0.023 nM and 1.47 nM, respectively. | ||
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