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RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC50s of 14.5 and 6.2 nM for ROCK1 and ROCK2, respectively. RKI 1447 dihydrochloride suppresses colorectal carcinoma cell growth and promotes apoptosis.
| Molecular Weight | 399.29 |
| CAS Number | 1782109-09-4 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
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Y-33075 hydrochloride (Y-39983) is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM. |
| SR-3677 dihydrochloride
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