About 30 results found for searched term "Pyr3" (0.039 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3876 | 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile | Others |
| 6-bromo-4-methoxypyrazolo[1,5-a]pyridine-3-carbonitrile | ||
| M3877 | 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | Others |
| 4-Chloro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine | ||
| M54751 | 2-Hydroxymethyl-5-hydroxypyridine | Others |
| 6-(Hydroxymethyl)pyridin-3-ol | ||
| 2-Hydroxymethyl-5-hydroxypyridine is isolated from the the matured, ripened and dried seeds of S. lychnophora. | ||
| M4424 | Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) | Apoptosis |
| Chuanxiongzine; Tetramethylpyrazine；Ligustrazine | ||
| Tetramethylpyrazine (2,3,5,6-Tetramethylpyrazine) is an alkyl pyrazine extracted from Ligusticum wallichii (Chuan Xiong), often used as a flavor in French fries, bread, tea, dairy products, bean products and other food. Ligustrazine has potential antineural and anti-inflammatory activities in rats. | ||
| M5043 | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | Others |
| 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine is an important pharmaceutical intermediate, which is widely used in the synthesis of many pharmaceutical intermediates at home and abroad. Including CP690550, CGP76030 and so on, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine was the scaffold for many commercially available drugs. Also, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine was the intermediate of the bulk drug, Tofatinib, which was widely used in treatment of adult patients with moderate to severe rheumatoid arthritis with inadequate or intolerant methotrexate response. | ||
| M8479 | Pyr6 | Others |
| N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide | ||
| Pyr6 is a selective inhibitor of calcium release from the endoplasmic reticulum via STIM1/Orai1 mediated, store operated calcium entry (SOCE). | ||
| M8978 | 3-TYP | Sirtuin |
| 3-(1H-1,2,3-triazol-4-yl) pyridine; 3TYP | ||
| 3-TYP is a selective SIRT3 inhibitor, more potent over SIRT1 and SIRT2, with IC50 values of 88 nM, 92 nM, 16 nM for SITR1, SIRT2, SIRT3, respectively. | ||
| M9034 | Mitapivat (AG-348) | Pyruvate Kinase |
| PKR-IN-1; PKM2 activator 1020; Pyrukynd； AG-348 | ||
| Mitapivat (AG-348) is the first-in-class, oral effective pyruvate kinase small molecule allosteric activator. Mitapivat (AG-348) is active against wild-type and various mutated PKR enzymes, and promotes healthy red blood cell generation by activating mutated PKR to increase ATP levels. | ||
| M9180 | Pyridostatin Trifluoroacetate Salt | DNA/RNA Synthesis |
| Pyridostatin TFA salt; PDS; CAS# 1085412-37-8(free base) | ||
| Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer, with a Kd of 490 nM. | ||
| M9668 | 6-chloropyrido[3,2-d]pyrimidine-2,4-diamine | Others |
| 6-chloropyrido[3,2-d]pyrimidine-2,4-diamine | ||
| M9672 | 5-Chloropyridazine-3,4-diamine | Others |
| 5-Chloropyridazine-3,4-diamine | ||
| M9680 | 3-Bromopyruvate (3-Bromopyruvic acid) | Others |
| Hexokinase II Inhibitor II; 3-BP | ||
| 3-Bromopyruvate (3-Bromopyruvic acid) is a hexokinase II inhibitor, which is an effective antitumor agent on the hepatoma cells. | ||
| M10197 | (Glp1)-Apelin-13 human, bovine | Apelin Receptor |
| [Pyr1]-Apelin-13 | ||
| (Glp1)-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. | ||
| M14286 | Pyr3 | TRP Channel |
| Pyr3 is a selective inhibitor of transient receptor potential canonical channel 3 (TRPC3), with an IC50 of 700 nM for TRPC3-mediated Ca2+ influx. | ||
| M15978 | 1,4-Dihydro-1-methyl-4-oxonicotinamide | Metabolite/Endogenous Metabolite |
| N-Methyl-4-pyridone-3-carboxamide | ||
| 1,4-Dihydro-1-methyl-4-oxonicotinamide is a metabolite of coffee pyridines, it is a useful organic compound for research related to life sciences. | ||
| M17923 | Cyclohexanecarboxylic acid, 3-[[ (2E)-3-[4-(D-glucopyranosyloxy)-3-hydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-, (1S,3R,4R,5R)- | Others |
| Cyclohexanecarboxylic acid, 3-[[（2E）-3-[4-（D-glucopyranosyloxy）-3-hydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-, （1S,3R,4R,5R）- | ||
| M17925 | β-D-glucopyranosyl 3-O-[ (O-β-D-xylopyranosyl-(1→2) (O-α-L-rhamnopyranosyl (1→3)β-D-glucuronopyranosyl]oleanolate | Others |
| β-D-glucopyranosyl 3-O-[（O-β-D-xylopyranosyl-（1→2） （O-α-L-rhamnopyranosyl（1→3）β-D-glucuronopyranosyl]oleanolate | ||
| M17926 | 2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester | Others |
| 2-Naphthalenecarboxylic acid, 4-（D-glucopyranosyloxy）-1-hydroxy-3-（3-hydroxy-3-methylbutyl）-, methyl ester | ||
| M17928 | (1β,2β,3β,4β,5β,7α,22α)-27-(β-D-Glucopyranosyloxy)-1,2,3,4,5,7,22-heptahydroxyfurost-25-en-6-one | Others |
| （1β,2β,3β,4β,5β,7α,22α）-27-（β-D-Glucopyranosyloxy）-1,2,3,4,5,7,22-heptahydroxyfurost-25-en-6-one | ||
| M17934 | 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-3-[ (4-methoxyphenyl)methyl]-, (R)- | Antibiotic |
| 4H-1-Benzopyran-4-one, 2,3-dihydro-3,5,7-trihydroxy-3-[（4-methoxyphenyl）methyl]-, （R）- | ||
| M17937 | Ophiogenin 3-O-α-L-rhamnopyranosyl (1→2)[β-D-xylopyranosyl (1→3)]-β-D-glucopyranoside | Others |
| Ophiogenin 3-O-α-L-rhamnopyranosyl（1→2）[β-D-xylopyranosyl（1→3）]-β-D-glucopyranoside | ||
| M17939 | 4H-1-Benzopyran-4-one,2,3-dihydro-5-hydroxy-3-[ (4-hydroxyphenyl)methyl]-7-methoxy- | Others |
| 4H-1-Benzopyran-4-one,2,3-dihydro-5-hydroxy-3-[（4-hydroxyphenyl）methyl]-7-methoxy- | ||
| M20472 | INCB032304 | Others |
| 4-(1h-pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy) methyl)-7h-pyrrolo[2,3-d]pyrimidine | ||
| deuterated derivatives of ruxolitinib | ||
| M30207 | 1-Acetyl-β-carboline | Others |
| 1-(9H-pyrido[3,4-b]indol-1-yl)ethanone | ||
| 1-Acetyl-β-carboline is metabolite of Nonomuraea endophytica. | ||
| M38882 | 5-Phenyl-1H-pyrazol-3-amine | Others |
| 5-Phenyl-1H-pyrazol-3-amine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M39682 | 2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one | Others |
| 2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one (Compound 2) is a pyranone isolated from the hexane extract of the aerial parts of Hypericum choisianum. | ||
| M40179 | Ethyl β-D-ribo-hexopyranosid-3-ulose | Others |
| Ethyl β-D-ribo-hexopyranosid-3-ulose (Compound 2) is a natural product that can be isolated from Coleus forskohlii. | ||
| M43850 | 2-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-2-azaspiro[3.3]heptane-6-acetic acid | Ligand for E3 Ligase |
| 2-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-2-azaspiro[3.3]heptane-6-acetic acid | ||
| M43853 | 1-(4-(piperidin-4-yl)phenyl)dihydropyrimidine-2,4(1H,3H)-dione | Ligand for E3 Ligase |
| 2,4(1H,3H)-Pyrimidinedione, dihydro-1-[4-(4-piperidinyl)phenyl]- | ||
| 1-(4-(piperidin-4-yl)phenyl)dihydropyrimidine-2,4(1H,3H)-dione | ||
| M43881 | 1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-3-pyrrolidinecarboxaldehyde | Ligand for E3 Ligase |
| 1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-3-pyrrolidinecarboxaldehyde | ||
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