About 16 results found for searched term "Peptidoglycan" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21611 | Peptidoglycan | Adjuvants |
| The peptidoglycan (murein) sacculus is a unique and essential structural element in the cell wall of most bacteria. This product is extracted from Bacillus subtilis. | ||
| M2009 | Teicoplanin | Antibiotic |
| MDL-507; Targocid; Teichomycin | ||
| Teicoplanin is a long-acting glycopeptide antibiotic derived from actinomycetes that inhibits cell wall synthesis and interferes with the process of synthesizing new portions of peptidoglycan, and has a good inhibitory effect on gram-positive pathogens (including staphylococcal biofilms). | ||
| M2391 | Ampicillin Trihydrate | Antibiotic |
| D-(-)-α-Aminobenzylpenicillin trihydrate | ||
| Ampicillin Trihydrate is a β-lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. | ||
| M4918 | Cefuroxime sodium | Antibiotic |
| Cefuroxime sodium salt | ||
| Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase-resistant, bactericidally active, second-generation cephalosporin antibiotic that inhibits the synthesis of the bacterial cell wall by inactivating penicillin-binding proteins (PBPs), which interferes with the final transpeptide step required to cross-link the peptidoglycan units, which are the building blocks of the cell wall which ultimately leads to cell lysis. | ||
| M5440 | Bacitracin | Anti-infection |
| Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis. | ||
| M7008 | Muramyl Dipeptide | p38 MAPK |
| MDP | ||
| Muramyl Dipeptide is a bacterial peptidoglycan fragment that activates NOD2 receptors. Muramyl Dipeptide induces polarization of proinflammatory Ly6Chigh into Ly6Clow patrolling monocytes. | ||
| M9667 | HADA hydrochloride | Anti-infection |
| HCC-Amino-D-alanine hydrochloride | ||
| HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation. | ||
| M19934 | Penicillin V potassium salt | Antibiotic |
| Phenoxymethylpenicillin potassium salt | ||
| Phenoxymethylpenicillin, also known as penicillin V, is an antibiotic useful for the treatment of a number of bacterial infections. It acts by inhibiting the biosynthesis of cell-wall peptidoglycan. | ||
| M21967 | Cefepime | Antibiotic |
| BMY-28142 | ||
| Cefepime is a semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. | ||
| M29450 | NADA-green | Fluorescent Dye |
| NADA hydrochloride | ||
| NADA-green is a fluorescent D-amino acid probe. NADA-green is efficiently incorporated into the peptidoglycan of diverse bacterial species peptidoglycan biosynthesis. NADA-green allows probing of bacterial growth with minimal perturbation. | ||
| M40727 | Teixobactin | Antibiotic |
| Teixobactin, a cyclic condensed peptide antibiotic isolated from the soil bacterium Eleftheria terrae, inhibits the synthesis of both peptidoglycan and teichoic acid, and exhibits antimicrobial activity against Gram-positive bacteria and Mycobacterium. | ||
| M45048 | Clovibactin | Antibiotic |
| Clovibactin, a novel antibiotic isolated from a soil bacterium and also a phenolphthalein condensate, is inhibitory to a wide range of drug-resistant Gram-positive bacteria, specifically inhibiting the membrane-associated steps of N-acetylglucosaminoglycans (GlcNAc) adherence to the cell wall, as well as the synthesis of peptidoglycan (PGN) and wall phosphatidylsulfonic acid (WTA), interfering with the synthesis of the cell wall and leading to cellular lysis. | ||
| M45212 | Mutanolysin | Others |
| Mutanolysin is an N-acetylcytoplasmic enzyme that cleaves the β-N-acetylcytoplasmic-(1→4)-N-acetylglucosamine bond of the bacterial cell wall polymer peptidoglycan polysaccharide, the carboxyl-terminal portion of which is associated with the recognition of, and binding to, the unique cell wall polymer.Mutanolysin cleaves Listeria monocytogenes and other Gram-positive bacteria (e.g., Lactobacillus spp. and Lactococcus spp.). In addition, Mutanolysin provides gentle cell lysis of readily degradable biomolecules and RNA from bacterial isolates, and can be used to form spheroplasts for DNA isolation. | ||
| M51221 | Ala-D-γ-Glu-Lys-D-Ala-D-Ala | Others |
| Ala-D-γ-Glu-Lys-D-Ala-D-Ala is the pentapeptide tail of the peptidoglycan precursor UDPMurNAc-l-Ala-γ-d-Glu-l-Lys(Gly)(5)-d-Ala-d-Ala. | ||
| M52628 | D-Ala-D-Ala | Metabolite/Endogenous Metabolite |
| D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. | ||
| M53593 | Amphomycin | Antibiotic |
| Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. | ||
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