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Cefepime

Cat. No. M21967

All AbMole products are for research use only, cannot be used for human consumption.

Cefepime Structure
Synonym:

BMY-28142

Size Price Availability Quantity
5mg USD 30  USD30 In stock
10mg USD 35  USD35 In stock
25mg USD 40  USD40 In stock
50mg USD 48  USD48 In stock
100mg USD 77  USD77 In stock
200mg USD 115  USD115 In stock
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Quality Control & Documentation
Biological Activity

Cefepime is a semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefepime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Chemical Information
Molecular Weight 480.56
Formula C19H24N6O5S2
CAS Number 88040-23-7
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Keith S Kaye, et al. JAMA. Effect of Cefepime/Enmetazobactam vs Piperacillin/Tazobactam on Clinical Cure and Microbiological Eradication in Patients With Complicated Urinary Tract Infection or Acute Pyelonephritis: A Randomized Clinical Trial

[2] Gozun Maan, et al. J Antimicrob Chemother. Cefepime-induced neurotoxicity: systematic review

[3] Gwendolyn M Pais, et al. Clin Pharmacokinet. Clinical Pharmacokinetics and Pharmacodynamics of Cefepime

[4] Jennifer Muradbegovic, et al. Rev Med Suisse. [Cefepime-induced encephalopathy]

[5] Danielle McDonald, et al. Am J Perinatol. Cefepime Dosing in Neonates: What is the Evidence?

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Keywords: Cefepime, BMY-28142 supplier, Antibiotic, inhibitors, activators

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