About 10 results found for searched term "OM-153" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M15067 | Recombinant Human FGF-4 (153AA, E.coli) | Cytokines and Growth Factors |
| Fibroblast growth factor 4; FGF-4; Heparin secretory-transforming protein 1 | ||
| Recombinant human fibroblast growth factor 4 is produced by the escherichia coli expression system and expresses the target gene encoding SER54-LEU206. Accession # : P08620. | ||
| M21589 | OM-153 | PARP |
| OM-153 is a potent, orally active tankyrase inhibitor with IC50 of 13 nM for tankyrase 1 and 2 nM for tankyrase 2 (TNKS1/2). OM-153 inhibited luciferase based Wnt/β-catenin signal transduction reporter activity with IC50 of 0.63 nM. OM-153 inhibits Wnt/β-catenin signal transduction and proliferation in COLO 320DM. | ||
| M1676 | BIBR1532 | Checkpoint |
| BIBR-1532 | ||
| BIBR1532 is a potent and selective telomerase inhibitor with IC50 of 100 nM. BIBR 1532 inhibits the proliferation of JVM13 leukemia cells with an IC50 of 52 μM, and similar effect also occurs in other leukemia cell lines such as Nalm-1, HL-60, and Jurkat. BIBR1532 is also an inhibitor of TERT, the rate-limiting enzyme in the regulation of telomerase activity. | ||
| M3229 | PR-104A | DNA/RNA Synthesis |
| PR-104A is a corresponding alcohol that is systemically converted from PR-104 and a hypoxia-targeted anticancer agent with IC50 of 153 and 60 μM for wild-type CHO AA8 under aerobic and anoxic conditions. | ||
| M3381 | Nevirapine | Reverse Transcriptase |
| BI-RG 587; NSC 641530; NVP | ||
| Nevirapine (NSC 641530) is a potent, specific non-nucleoside reverse transcriptase inhibitor (NNRTIs) that non-competitively inhibits human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with a Ki of 220 nM. Nevirapine (NSC 641530) can be used in AIDS-related researchs. | ||
| M11386 | Recombinant Human CD19 Protein (HEK293) | Cytokines and Growth Factors |
| Recombinant Human CD19 Protein (HEK293) Protein sequence: THE DNA sequence encoding human CD19 (UniProtKB/ Swiss-PROt: P15391.6) was expressed with His tag at the C-terminal. Bioactivity: Immobilized CD19 monoclonal antibody at 5μg/mL (100 μL/ well) can bind CD19 protein in a linear range of 5-100ng/mL | ||
| M21142 | MK-8153 | Potassium Channel |
| MK-8153 is a potent, selective and orally active extrarenal medullary potassium channel (ROMK) inhibitor with IC50 values of 5 nM and 34 μM for ROMK EP and hERG EP, respectively.MK-8153 can be used as a diuretic. | ||
| M42743 | ALPK1-IN-3 | NF-κB |
| ALPK1-IN-3 is an inhibitor of ALPK1 extracted from patent WO2022063153A1 compound T007. | ||
| M45317 | (S)-BAY 2965501 | DGK |
| (S)-BAY 2965501 is the left-handed isomer of BAY 2965501 (HY-153343).BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKz) inhibitor and induces pERK activation. BAY 2965501 is a potent and selective inhibitor of diacylglycerol kinase zeta (DGKz) and induces pERK activation. | ||
| M56168 | Antisauvagine-30 | CRFR |
| Antisauvagine-30 (aSvg-30) is a potent, competitive and selective CRF2 receptor antagonist with Kd values of 1.4 nM and 153.6 nM for mouse CRF2β and rat CRF1 receptors, respectively. | ||
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