About 11 results found for searched term "MPO-IN-28" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20766 | MPO-IN-28 | Others |
| MPO-IN-28 (Compound 28) is an inhibitor of myeloperoxidase (MPO) with IC50 of 44 nM. | ||
| M1602 | SR1664 | PPAR |
| SR 1664 | ||
| SR1664 is an antidiabetic compound that binds to PPARγ and can effectively inhibit CDK5-mediated phosphorylation of PPARγ with IC50 of 80 nM and Ki of 28.67 nM. | ||
| M6284 | Compound 401 | DNA-PK |
| Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro. | ||
| M14162 | Cot inhibitor-1 | p38 MAPK |
| Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC50 of 5.7 nM. | ||
| M21331 | Recombinant Human CDH1 (HEK293, C-6His) | Cytokines and Growth Factors |
| Cadherin-1; CDH1;CAM 120/80;E-cadherin; CD324 | ||
| Recombinant human Cadherin-1/E-Cadherin/CDH1 is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. Accession: P12830. | ||
| M27769 | Lin28-let-7 antagonist 1 | Others |
| Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells. | ||
| M28691 | DprE1-IN-2 | Antibiotic |
| DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect. | ||
| M29603 | FAK inhibitor 6 | FAK |
| Compound 26F not only optimized the effective inhibitory enzyme (ic50= 28.2 nm), but also showed relatively less cytotoxicity (ic50= 3.32 μ M) And induced MDA-MB-231 cell apoptosis in a dose-dependent manner, effectively blocking MDA-MB-231 cells in g0/g1 phase. | ||
| M30315 | PRL-3 Inhibitor 2 | Phosphatase |
| PRL-3 Inhibitor 2 (compound 2) is a potent PRL-3 inhibitor with an IC50 value of 28.1 µM. | ||
| M30973 | (S)-BI-1001 | Others |
| (S)-BI-1001 (Compound 11) is an active S-enantiomer of BI-1001. (S)-BI-1001 exhibits antiviral potency against HIV-1 integrase with an IC50 of 28 nM, an EC50 of 450 nM and a Kd of 4.7 μM. | ||
| M55036 | Belatacept | Immunology/Inflammation |
| BMS 224818; LEA 29Y | ||
| Belatacept (BMS 224818) is a fusion protein composed of the Fc fragment of a human IgG1 immunoglobulin linked to the extracellular domain of CTLA-4, which is a molecule crucial in the regulation of T cell costimulation, selectively blocking the process of T-cell activation. Belatacept binds to CD 80/86 ligands and thereby inhibits the CD-28-mediated T-cell costimulation. Belatacept can be used in the research of Immunosuppression in organ transplants. | ||
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