About 7 results found for searched term "Heparan Sulfate" (0.179 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9544 | Heparan Sulfate | Wnt/beta-catenin |
| Heparan sulfate is a complex and linear polysaccharide, which expressed abundantly on the cell surface and in the extracellular matrix. | ||
| M15073 | Recombinant Human HGF (HEK293, C-6His) | Cytokines and Growth Factors |
| Hepatocyte growth factor; HPTA; Scatter factor | ||
| HGF is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. | ||
| M15076 | Recombinant Mouse HGF (HEK293,C-6His) | Cytokines and Growth Factors |
| Hepatopoietin-A;Scatter factor;SF;deafness, autosomal recessive 39 | ||
| Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. | ||
| M24945 | Pabinafusp alfa | Others |
| JR-141 | ||
| Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice. | ||
| M25116 | Lepunafusp alfa | Others |
| JR-171 | ||
| Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I. | ||
| M30269 | Surfen dihydrochloride | FGFR |
| Aminoquincarbamide dihydrochloride | ||
| Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection. | ||
| M57280 | β-N-methylamino-L-alanine hydrochloride | Others |
| S(+)-2-Amino-3-(methylamino)propionic acid hydrochloride | ||
| β-N-methylamino-L-alanine hydrochloride (BMAA hydrochloride) is a neurotoxin produced by cyanobacteria. L-BMAA hydrochloride helps to block the addition of heparan sulfate to glypican-1. It possesses unusual glutamate receptor binding properties. | ||
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