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Heparan Sulfate

Cat. No. M9544
Heparan Sulfate Structure
Size Price Availability Quantity
5mg USD 110  USD110 In stock
10mg USD 160  USD160 In stock
25mg USD 340  USD340 In stock
50mg USD 520  USD520 In stock
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Quality Control & Documentation
  • Purity: Potency ≥60IU/MG, BR
  • COA
  • MSDS
Biological Activity

Heparan sulfate is a complex and linear polysaccharide, which expressed abundantly on the cell surface and in the extracellular matrix.

Chemical Information
Molecular Weight 593.47
Formula C12H19NO20S3 (monomer)
CAS Number 9050-30-0
Solubility (25°C) Water ≥ 35 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Yona Nadir. Effect of Heparanase and Heparan Sulfate Chains in Hemostasis

[2] Alejandro Gmez Toledo, et al. A Systems View of the Heparan Sulfate Interactome

[3] Mohit Chhabra, et al. PI-88 and Related Heparan Sulfate Mimetics

[4] Barbara Bartolini, et al. Heparan Sulfate in the Tumor Microenvironment

[5] J-P Li, et al. Heparan Sulfate: Biosynthesis, Structure, and Function

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Keywords: Heparan Sulfate supplier, Wnt/beta-catenin, inhibitors, activators

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