About 17 results found for searched term "Glycine-d2" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M55428 | Glycine-d2 | GluR |
| Glycine-d2 | ||
| M55530 | N-Carbobenzyloxyglycine-d2 | Amino Acid Derivatives |
| N-Carbobenzyloxyglycine-d2 | ||
| M5464 | Bitopertin | GlyT |
| RG1678, RO-4917838 | ||
| Bitopertin (RG1678,RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells. | ||
| M8733 | K67 | Keap1-Nrf2 |
| K-67 | ||
| K67 is a specific inhibitor against the interaction between KEAP1 (Kelch-like ECH-associated protein 1) DC (double glycine repeat and C-terminal region) domain and S349-phosphorylated (human Ser349, mouse Ser351) KIR (Keap1-interacting region) of p62/SQSTM1, thereby preventing phospho-p62 from blocking KEAP1-DC and NRF2 (nuclear factor erythroid 2-related factor 2) DLGex motif association. | ||
| M25421 | NNZ-2591 | Peptides |
| NNZ-2591 is a synthetic analogue of a small peptide of cyclic glycine proline (cGP). NNZ-2591 shows orally active and cross the blood-brain barrier. NNZ-2591 shows neuroprotective after ischemic brain injury. | ||
| M27829 | CGP 78608 hydrochloride | GluR |
| CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). Anticonvulsant activity. | ||
| M27836 | PAOPA | Dopamine Receptor |
| PAOPA, an analog of L-proline-l-leucine-glycine amide (PLG) peptide, is an allosteric modulator of Dopamine D2 Receptor. PAOPA can effectively reduce behavioral abnormalities in rodent models of schizophrenia. PAOPA increases the high affinity dopamine D2 receptor and promotes its binding to agonists. | ||
| M28598 | PYD-106 | GluR |
| PYD-106 is a stereoselective pyrrolidinone (PYD) positive allosteric modulator for GluN2C-containing NMDA receptors. PYD-106 increases opening frequency and open time of single channel currents activated by maximally effective concentrations of agonist but only has modest effects on glutamate and glycine EC50. PYD-106 selectively enhances the responses of diheteromeric GluN1/GluN2C receptors but not triheteromeric GluN1/GluN2A/GluN2C receptors. | ||
| M30961 | Org 25935 | GlyT |
| Org 25935 is a potent and selective glycine transporter 1 protein (GlyT1) inhibitor with an IC50 value of 100 nM. Org 25935 can decrease ethanol (EtOH) intake and EtOH preference in rats, whereas water intake is unaffected. Org 25935 can be used for researching alcohol dependence or abuse. | ||
| M31102 | Tricine | Solvents & Excipients |
| N-tris(hydroxymethyl)methylglycine | ||
| N-tris(hydroxymethyl)methylglycine is a Good's buffer substance, pKa = 8.15 at 20 ℃. | ||
| M39103 | 2-Phenylglycine | Metabolite/Endogenous Metabolite |
| 2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the W2 to W4 lactation period. | ||
| M43192 | Glycylhistidylglycine | Others |
| Glycylhistidylglycine is composed of two glycines and one histidine, which can detect and remove the concentration of Cu2+ ions in wastewater by forming a tripeptide complex with copper and nickel ions. | ||
| M45379 | Trofinetide | Peptides |
| NNZ-2566 | ||
| Trofinetide, a water-soluble analog of glycine-proline-glutamic acid (GPE), uses the unnatural amino acid 2-methylproline in place of the proline found in the natural compound, and works by enhancing synaptic activity, restoring synaptic structure, inhibiting the effects of inflammatory compounds in the brain, increasing antioxidant responses, reducing injury-induced cell death, and increasing central IGF-1 presence. It has neuroprotective activity and can be used in studies related to Rett syndrome. | ||
| M52002 | Z-D-Phg-OH | Amino Acid Derivatives |
| Z-D-Phg-OH (D-Cbz phenylglycine) is a N-blocked amino acids with Kd values of 390 μM and 323 μM for tBuCQN and tBuCQD, respectively. | ||
| M52868 | 2-(3-Trifluoromethylphenyl)glycine hydrochloride | Vasopressin Receptor |
| 2-(3-Trifluoromethylphenyl)glycine hydrochloride is a precursor of substituted 2-acetamido-5-aryl-l, 2,4-triazolones. | ||
| M55324 | N-Oxalylglycine | Others |
| N-Oxaloglycine | ||
| N-Oxalylglycine (N-Oxaloglycine) is a broad-spectrum 2-oxoglutarate oxygenase inhibitor. | ||
| M55411 | N-Arachidonylglycine | Metabolite/Endogenous Metabolite |
| NAGLY; NA-Gly | ||
| N-Arachidonylglycine (NA-Gly) is a GPR18 agonist (EC50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration. | ||
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