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N-Oxalylglycine

Cat. No. M55324
N-Oxalylglycine Structure
Synonym:

N-Oxaloglycine

Size Price Availability Quantity
10mg USD 25  USD25 In stock
50mg USD 35  USD35 In stock
100mg USD 45  USD45 In stock
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Quality Control & Documentation
Biological Activity

N-Oxalylglycine (N-Oxaloglycine) is a broad-spectrum 2-oxoglutarate oxygenase inhibitor. N-Oxalylglycine can be used in studies on the hypoxic response and chromatin modifications in animals.

Chemical Information
Molecular Weight 147.09
Formula C4H5NO5
CAS Number 5262-39-5
Solubility (25°C) Water 80 mg/mL
Storage 4°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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  Catalog
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