About 8 results found for searched term "GPR119 agonist 2" (0.118 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41841 | GPR119 agonist 2 | GPR/FFAR |
| GPR119 agonist 2 is an orally active GPR119 agonist. | ||
| M3321 | GSK1292263 | GPR/FFAR |
| GSK1292263 is a novel GPR119 agonist, showing potential for the treatment of type 2 diabetes. | ||
| M3632 | MBX-2982 | GPR/FFAR |
| MBX2982 | ||
| MBX-2982 is a selective, orally-available GPR119 agonist for the treatment of type 2 diabetes. | ||
| M3950 | APD668 | GPR/FFAR |
| APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively. APD668 pairs are divided by CYP2C9 (KiNone of the five major CYP subtypes other than =0.1 μM) had no significant inhibitory effect. APD668 can be used for research on steatohepatitis and diabetes. | ||
| M5040 | APD597 | GPR/FFAR |
| JNJ 38431055 | ||
| APD597 (JNJ-38431055) is a GPR119 agonist used in the study of type 2 diabetes mellitus. The EC50 of hGPR119 is 46 nM. | ||
| M6466 | AS 1269574 | GPR/FFAR |
| AS1269574 is a potent, orally active GPR119 agonist with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates the TRPA1 cation channel and stimulates glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induced pancreatic β cells to secrete glucose-dependent insulin only under high glucose conditions. AS1269574 has potential for type 2 diabetes research. | ||
| M25489 | 2-Oleoylglycerol | GPR/FFAR |
| 2-Oleoylglycerol is a GPR119 agonist, with an EC50 of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo. | ||
| M27673 | GSK2041706A | GPR/FFAR |
| GSK706 | ||
| GSK2041706A (GSK706) is a potent G protein-coupled receptor 119 (GPR119) agonist. GSK2041706A can be used for the research of type 2 diabetes. | ||
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