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APD597

Cat. No. M5040

All AbMole products are for research use only, cannot be used for human consumption.

APD597 Structure
Synonym:

JNJ 38431055

Size Price Availability Quantity
10mM*1mL in DMSO USD 88  USD88 In stock
5mg USD 80  USD80 In stock
10mg USD 140  USD140 In stock
25mg USD 240  USD240 In stock
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Quality Control & Documentation
Biological Activity

APD597 (JNJ-38431055) is a GPR119 agonist used in the study of type 2 diabetes mellitus. The EC50 of hGPR119 is 46 nM. APD597 was selected for preclinical development based on the good balance between agonist potency and intrinsic activity, especially its good solubility and potential to reduce compound - compound interactions.

Chemical Information
Molecular Weight 479.55
Formula C21H29N5O6S
CAS Number 897732-93-3
Form Solid
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Buzard DJ,et.al. Bioorg Med Chem Lett. Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists.

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  Catalog
Abmole Inhibitor Catalog




Keywords: APD597, JNJ 38431055 supplier, GPR/FFAR, inhibitors, activators

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