About 12 results found for searched term "GLUT1-IN-3" (0.212 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42902 | GLUT1-IN-3 | Others |
| GLUT1-IN-3, an investigational compound associated with type 1 glucose transporter deficiency syndrome, potently suppresses seizures. | ||
| M1601 | Dulaglutide (Activated main chain) | GLP Receptor |
| Dulaglutide (Activated main chain) is a glucagon-like peptide-1 receptor agonist (GLP-1 agonist) consisting of GLP-1(7-37) covalently linked to an Fc fragment of human IgG4. | ||
| M4970 | STF-31 | GLUT |
| STF-31 is a selective glucose transporter GLUT1 inhibitor, with an IC50 of 1 μM. STF-31 is also a NAMPT inhibitor. | ||
| M7778 | Dantrolene sodium salt | Calcium Channel |
| F 440 | ||
| Dantrolene sodium is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 μM and an IC50 of 52.3 μM. Dantrolene sodium is also a calcium channel protein inhibitor. Dantrolene sodium inhibits the release of Ca2+ from RyR1 and RyR3, which can be beneficial in a variety of pathologies caused by disruptions in calcium homeostasis. | ||
| M10744 | V-9302 | Others |
| V9302 | ||
| V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells. | ||
| M14444 | GSTO1-IN-1 | Others |
| GSTO1-IN-1 is a potent glutathione S-transferase omega 1 (GSTO1) inhibitor with an IC50 of 31 nM. | ||
| M21510 | Telaglenastat hydrochloride | Others |
| CB-839 hydrochloride | ||
| Telaglenastat (CB-839) hydrochloride is a pioneering (first-in-class), selective, reversible, orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride has IC50 values of 23 nM and 28 nM for endogenous glutaminase in the kidney and brain of mice, respectively. Telaglenastat hydrochloride also induces autophagy and has strong antitumor activity. | ||
| M28422 | TASP0433864 | GluR |
| TASP0433864 is a selective positive allosteric modulator (PAM) of metabotropic glutamate 2 (mGlu2) receptor with EC50 values of 199 nM and 206 nM against human and rat mGlu2 receptors, respectively. TASP0433864 has antipsychotic activity. | ||
| M30802 | iGOT1-01 | Others |
| iGOT1-01 is a potent aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1; GOT1) inhibitor. iGOT1-01 has IC50s of 85 μM and 11.3 μM in MDH coupled GOT1 enzymatic assay and GOT1/GLOX/HRP assay, respectively. iGOT1-01 has anti-cancer activity. | ||
| M49462 | GPX4-IN-3 | Ferroptosis |
| GPX4-IN-3 is a potent glutathione peroxidase 4 (GPX4) inhibitor that selectively induces ferroptosis.1 μM of GPX4-IN-3 inhibited 71.7% of GPX4 activity. | ||
| M53176 | GLP-1 moiety from Dulaglutide | Glucagon Receptor |
| GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist, extracted from patent US 20160369010 A1. | ||
| M54563 | GLUT inhibitor-1 | GLUT |
| GLUT inhibitor-1 is a potent and orally active glucose transporter protein (GLUT) inhibitor that targets GLUT1 and GLUT3 with IC50 values of 242 nM and 179 nM, respectively.GLUT inhibitor-1 can be used in cancer and autoimmune disease related studies. | ||
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