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Telaglenastat hydrochloride

Cat. No. M21510

All AbMole products are for research use only, cannot be used for human consumption.

Telaglenastat hydrochloride Structure
Synonym:

CB-839 hydrochloride

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Quality Control & Documentation
Biological Activity

Telaglenastat (CB-839) hydrochloride is a pioneering (first-in-class), selective, reversible, orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride has IC50 values of 23 nM and 28 nM for endogenous glutaminase in the kidney and brain of mice, respectively. Telaglenastat hydrochloride also induces autophagy and has strong antitumor activity.

Chemical Information
Molecular Weight 608.04
Formula C26H25ClF3N7O3S
CAS Number 1874231-60-3
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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Keywords: Telaglenastat hydrochloride, CB-839 hydrochloride supplier, inhibitors, activators

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