About 16 results found for searched term "EGLU" (0.063 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2306 | Tideglusib | GSK-3 |
| NP-12; NP031112 | ||
| Tideglusib (NP031112, NP-12) is a potent non ATP-competitive inhibitor of GSK3 with IC50 of 60 nM. | ||
| M2712 | Fosaprepitant dimeglumine salt | Neurokinin Receptor |
| MK-0517 dimeglumine salt; L-758,298 dimeglumine salt | ||
| Fosaprepitant is a water-soluble phosphoryl procompound for Aprepitant which is a NK1 antagonist.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M5380 | Aceglutamide | Autophagy |
| α-N-Acetyl-L-glutamine, N2-Acetylglutamine | ||
| Aceglutamide is a precursor compound to glutamine that improves nerve cell metabolism. | ||
| M5655 | Flunixin Meglumin | COX |
| Flunixin Meglumin is a potent inhibitor of the enzyme cyclooxygenase used as analgesic agent with anti-inflammatory and antipyretic activity. | ||
| M6702 | EGLU | Others |
| EGLU is a highly selective group II mGlu antagonist. | ||
| M6935 | LY 354740 | Others |
| Eglumegad; Eglumetad | ||
| LY 354740 is a potent and highly selective group II mGlu agonist. | ||
| M9732 | Gadopentetate dimeglumine | Others |
| Gadopentetic acid dimeglumine salt | ||
| Gadopentetate dimeglumine is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on the MRI. | ||
| M14778 | Tafamidis meglumine | Transthyretin (TTR) |
| Fx-1006A | ||
| Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. | ||
| M19870 | Delafloxacin Meglumine | Antibiotic |
| ABT-492; RX-3341; WQ-3034; Baxdela | ||
| Delafloxacin (ABT-492, RX-3341, WQ-3034, Baxdela) meglumine is a broad-spectrum fluoroquinolone antibiotic against multiple pathogens. | ||
| M22472 | Insulin degludec | Insulin Receptor |
| Insulin degludec is an ultra-long-acting form of insulin, shows binding efficiency with an IC50 value of 19.59 nM/L for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes. | ||
| M31217 | Utreglutide | GLP Receptor |
| GL0034 | ||
| Utreglutide is a potent glucagon-like peptide 1 (GLP-1) receptor agonit. | ||
| M40866 | Meglutol | HMG-CoA Reductase |
| Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid | ||
| Meglutol is an antilipidemic agent that lowers cholesterol, triglycerides, serum beta-lipoproteins, and phospholipids, and inhibits the activity of the rate-limiting enzyme of cholesterol biosynthesis, HMG-CoA reductase. | ||
| M41872 | Eglumegad hydrochloride | GluR |
| Eglumegad (LY354740) hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. | ||
| M43952 | Hymeglusin | Antibiotic |
| Hymeglusin is a β-lactone antibiotic with antifungal activity and an HMG-CoA synthase inhibitor with an IC50 value of 0.12 μM, which can inhibit HMG-CoA synthase by covalently modifying the active Cys129 residue of the enzyme. | ||
| M44821 | Crocetin meglumine | GluR |
| Crocetin (Transcrocetin) meglumine, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. | ||
| M56268 | Raseglurant hydrochloride | GluR |
| Raseglurant hydrochloride is a negative allosteric modulator of mGluR5. | ||
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