All AbMole products are for research use only, cannot be used for human consumption.
Meglutol is an antilipidemic agent that lowers cholesterol, triglycerides, serum beta-lipoproteins, and phospholipids, and inhibits the activity of the rate-limiting enzyme of cholesterol biosynthesis, HMG-CoA reductase.
| Molecular Weight | 162.14 |
| Formula | C6H10O5 |
| CAS Number | 503-49-1 |
| Form | Solid |
| Solubility (25°C) | DMSO > 250 mg/mL |
| Storage | -20°C |
[2] Dylan E Jones et al. Clin Chim Acta. 3-Methylglutaric acid in energy metabolism
[3] I Yoshida. Ryoikibetsu Shokogun Shirizu. [3-Hydroxy-3-methylglutaryl-CoA-lyase deficiency]
[4] T Lerman-Sagie. Pediatr Neurol. Behr syndrome
[5] C L Greene et al. J Neurogenet. 3-Hydroxy-3-methylglutaric aciduria
| Related HMG-CoA Reductase Products |
|---|
| Dalvastatin
Dalvastatin (RG-12561) inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis. |
| (3S,5R)-Fluvastatin sodium
(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. |
| Fluvastatin
Fluvastatin is the first fully synthesized, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin protects vascular smooth muscle cells from oxidative stress through an Nrf2-dependent antioxidant pathway. |
| Pravastatin lactone
Pravastatin lactone is a potent HMG-CoA inhibitor. |
| HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. |
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