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Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis meglumine inhibits amyloidogenesis.
| Molecular Weight | 503.33 |
| CAS Number | 951395-08-7 |
| Storage | 2-8°C, dry, sealed |
[2] No authors listed. Tafamidis and tafamidis meglumine for amyloid cardiomyopathy
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