About 7 results found for searched term "C75" (0.106 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1812 | GANT58 | Gli |
| NSC75503 | ||
| GANT58 (NSC75503) is a potent GLI antagonist that inhibits GLI1-induced transcription with an IC50 of 5 μM. | ||
| M2076 | SP600125 | JNK |
| JNK Inhibitor II; 1PMV; NSC75890; Pyrazolanthrone | ||
| SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM. | ||
| M2604 | C75 | FAS |
| C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS). C75 inhibits prostate cancer cells PC3 with an IC50 of 35 μM. C75 is a potent CPT1A activator. | ||
| M4940 | SC75741 | NF-κB |
| SC-75741 | ||
| SC75741 is a broad and potent INHIBITOR of NF-κB with an IC50 of 200 nM against P65. SC75741 blocks replication of influenza viruses. SC75741 leads to decreased expression of cytokines, chemokines, and pro-apoptotic factors by impairing DNA binding of NF-κB subunit P65. Inhibit caspase activation and block caspase-mediated nuclear output of viralribonucleoproteins. | ||
| M8493 | NSC756093 | Others |
| NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction that inhibits proliferation of paclitaxel resistant cancer cells. | ||
| M9508 | C75 trans | FAS |
| (±)-C75 | ||
| C75 trans is an enantiomer of C75, which is a synthetic fatty-acid synthase (FASN) inhibitor. | ||
| M13554 | LDC7559 | Pyroptosis |
| LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages . | ||
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