C75 - Search Results | AbMole BioScience

About 7 results found for searched term "C75" (0.077 seconds)

Cat.No.	Name	Target
M1812	GANT58	Gli
	NSC75503
	GANT58 (NSC75503) is a potent GLI antagonist that inhibits GLI1-induced transcription with an IC50 of 5 μM.
M2076	SP600125	JNK
	JNK Inhibitor II; 1PMV; NSC75890; Pyrazolanthrone
	SP600125 is a novel and selective inhibitor of c-Jun N-terminal kinase (JNK), inhibited phosphorylation of c-Jun with an IC50 of 5-10 microM.
M2604	C75	FAS
	C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS). C75 inhibits prostate cancer cells PC3 with an IC50 of 35 μM. C75 is a potent CPT1A activator.
M4940	SC75741	NF-κB
	SC-75741
	SC75741 is a broad and potent INHIBITOR of NF-κB with an IC50 of 200 nM against P65. SC75741 blocks replication of influenza viruses. SC75741 leads to decreased expression of cytokines, chemokines, and pro-apoptotic factors by impairing DNA binding of NF-κB subunit P65. Inhibit caspase activation and block caspase-mediated nuclear output of viralribonucleoproteins.
M8493	NSC756093	Others
	NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction that inhibits proliferation of paclitaxel resistant cancer cells.
M9508	C75 trans	FAS
	(±)-C75
	C75 trans is an enantiomer of C75, which is a synthetic fatty-acid synthase (FASN) inhibitor.
M13554	LDC7559	Pyroptosis
	LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages .