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NSC756093

Cat. No. M8493

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NSC756093 Structure
Size Price Availability Quantity
5mg USD 115  USD115 In stock
10mg USD 195  USD195 In stock
25mg USD 420  USD420 In stock
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Quality Control & Documentation
Biological Activity

NSC756093, a podophyllotoxin analog, is a potent and specific inhibitor of GBP1:PIM1 interaction that inhibits proliferation of paclitaxel resistant cancer cells. Apparently, NSC756093 stabilizes a conformation of GBP1 not suitable for binding to PIM1.

Chemical Information
Molecular Weight 337.37
Formula C20H19NO4
CAS Number 1629908-92-4
Solubility (25°C) DMSO: 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mirko Andreoli, et al. Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells

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Keywords: NSC756093 supplier, inhibitors, activators

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