About 30 results found for searched term "C-106" (0.045 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1765 | Crizotinib (PF-02341066) | c-Met |
| Crizotinib | ||
| Crizotinib (PF-02341066) is a potent, orally bioavailable, ATP-competitive small-molecule inhibitor of c-Met kinase and ALK (anaplastic lymphoma kinase) with IC50 values to be 4 and 25 nM for C-Met and ALK resepectively. | ||
| M2259 | Biapenem | Antibiotic |
| L-627; LJC 10627; CLI 86815 | ||
| Biapenem is a new parenteral carbapenem antibacterial agent with a broad spectrum of in vitro antibacterial activity. | ||
| M3963 | Bruceine A | NF-κB |
| Dihydrobrusatol; NSC310616 | ||
| Brucaine A (Brucea javanica A) is a natural bitter bitter compound, extracted from the dried fruit of Brucea javanica, which can act on dog scorch. | ||
| M3480 | Tolvaptan | Vasopressin Receptor |
| OPC-41061 | ||
| Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation. | ||
| M3888 | CAY10603 (BML-281) | HDAC |
| BML-281; Isox | ||
| CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM. | ||
| M4477 | Costunlide | Apoptosis |
| (+)-Costunolide; Costunolid; Costus lactone; NSC 106404 | ||
| Costunlide | ||
| M5199 | Santacruzamate A | HDAC |
| CAY10683 | ||
| Santacruzamate A is a picomolar level selective inhibitor of HDAC2 with an IC50 of 85.8 nM, a Class I HDAC, with relatively little inhibition of HDAC4 or HDAC6, both Class II HDACs. | ||
| M5244 | Ozanimod | S1P Receptor |
| RPC1063 | ||
| Ozanimod (RPC1063) is a selective, orally active sphingosine-1-phosphate (S1P) receptor modulator that binds to S1PR1 and S1PR5, and can be used in studies related to ulcerative colitis (UC). | ||
| M6171 | Solithromycin | Antibiotic |
| CEM-101; OP-1068 | ||
| Solithromycin is a novel fluoroketolide with improved antimicrobial effectiveness. | ||
| M6391 | AC 261066 | Others |
| AC 261066 is a rARβ2 agonist. | ||
| M7374 | TC-H 106 | HDAC |
| Pimelic Diphenylamide 106; RGFA-8; Histone Deacetylase Inhibitor VII | ||
| TC-H 106 is a class I histone deacetylase inhibitor, with IC50 values of 150 nM , 760 nM and 370 nM for HDAC 1, 2, and 3, respectively. | ||
| M9496 | Balaglitazone | PPAR |
| DRF-2593; NN-2344; NNC-610645 | ||
| Balaglitazone is an agonist of peroxisome proliferator-activated receptor (PPAR) γ, with an EC50 of 1.351 μM for human PPARγ. | ||
| M10268 | CID-1067700 (ML282) | Ras |
| CID-1067700 | ||
| CID-1067700 (ML282) is a competitive inhibitors of nucleotide binding by Ras-related GTPases with a Ki of 13 nM for Rab7. | ||
| M10295 | CAY10602 | Sirtuin |
| CAY-10602 | ||
| CAY10602 is a SIRT1 activator, which suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells dose-dependently. | ||
| M13412 | Ethynylcytidine | DNA/RNA Synthesis |
| ECyD; TAS-106; 3'-C-Ethynylcytidine | ||
| Ethynylcytidine is a new nucleoside antimetabolite. A potent inhibitor of RNA synthesis, Ethynylcytidine has demonstrated strong antitumor activity in a variety of cancer models. | ||
| M14509 | CAY10650 | Phospholipase |
| CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. CAY10650 suppresses lipid droplets formation and PGE2 secretion. | ||
| M14754 | Pimelic Diphenylamide 106 (analog) | Others |
| RGFA-8 analog; TC-H 106 analog | ||
| Pimelic Diphenylamide 106 analog is an analog of Pimelic Diphenylamide 106 with unknown biological activity. | ||
| M19933 | Amdinocillin | Antibiotic |
| Mecillinam; Coactin; FL 1060 | ||
| Amdinocillin (Mecillinam, Coactin, FL 1060) is a β-lactam antibiotic with a broad spectrum of antibacterial activity. Amdinocillin is active alone against many gram-negative organisms. | ||
| M21722 | Felezonexor (CBS9106) | CRM1 |
| CBS9106; SL-801 | ||
| Felezonexor (CBS9106; SL-801) is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity without affecting CRM1 mRNA levels. Felezonexor is also a reversible inhibitor of XPO1, inhibits nuclear export by covalently binding to Cys528 as well as by inducing the degradation of XPO1. | ||
| M22105 | CAY10680 | Others |
| CAY10680 | ||
| M22135 | CAY10648 | Others |
| CAY10648 | ||
| M25234 | Balugrastim | Others |
| CG 10639 | ||
| Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer. | ||
| M27930 | GPP78 | NAMPT |
| CAY10618 | ||
| GPP78 (CAY10618) is a potent Nampt inhibitor with an IC50 of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC50 of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects. | ||
| M28696 | Ozanimod hydrochloride | S1P Receptor |
| RPC-1063 hydrochloride | ||
| Ozanimod (RPC-1063) hydrochloride, a sphingosine 1-phosphate (S1P) receptor modulator that binds with high affinity selectively to S1P receptor subtypes 1 (S1P1) and 5 (S1P5). Ozanimod hydrochloride has modulate effect for hS1P1 and hS1P5 receptor with EC50s of 1.03 nM and 8.6 nM, respectively. Ozanimod hydrochloride can be used for the research of relapsing multiple sclerosis (MS) . | ||
| M30509 | Rachelmycin | Antibiotic |
| CC-1065; NSC 298223 | ||
| Rachelmycin (CC-1065) is an antitumor antibiotic and a DNA-alkylating agent. Rachelmycin has cytotoxic potency that can be used as a cytotoxin to synthesis ADC. Rachelmycin effectively inhibits DNA synthesis. Rachelmycin can be used for cancer and infection research. | ||
| M31170 | MSC-4106 | YAP |
| MSC-4106 is an orally active inhibitor of the YAP/TAZ-TEAD complex that blocks the auto-palmitoylation of TEAD1 and TEAD3, and can be used for tumor-related studies. | ||
| M49413 | C-106 | Angiotensin Receptor |
| C-106 is an angiotensin II-2 type 2 receptor (AT2R) agonist that may be used in studies related to idiopathic pulmonary fibrosis (IPF). | ||
| M49919 | Recombinant Human VCAM-1 Protein (HEK293, C-6His) | Cytokines and Growth Factors |
| Vascular Cell Adhesion Protein 1; V-CAM 1 | ||
| VCAM-1 is a single-pass type I membrane protein, and mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. | ||
| M49922 | Recombinant Human VCAM-1 Protein (HEK293, C-Fc) | Cytokines and Growth Factors |
| Vascular Cell Adhesion Protein 1; V-CAM 1 | ||
| VCAM-1 is a single-pass type I membrane protein, and mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. | ||
| M51188 | K-Casein (106-116), bovine | Others |
| K-Casein (106-116),bovine is a peptide that inhibits platelet aggregation and fibrinogen binding, plays an important role in atherosclerosis. | ||
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