About 8 results found for searched term "56-40-6" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3257 | Torsemide | Others |
| Torasemide | ||
| Torsemide is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 ± 0.17 μM. | ||
| M9566 | Glycine | GluR |
| Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate. | ||
| M24893 | Mitazalimab | TNF Receptor |
| ADC-1013; JNJ-64457107 | ||
| Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment. | ||
| M39504 | Fmoc-Phe-OH | Amino Acid Derivatives |
| Fmoc-Phe-OH is a phenylalanine derivative. | ||
| M25003 | Talquetamab | Others |
| JNJ-64407564 | ||
| Talquetamab (JNJ-64407564) is a potentially first-in-class humanized IgG4ҡ/λ bispecific antibody that binds to GPRC5D (G-protein-coupled receptor family, group C5, member D) and CD3, and induces T-cell-mediated by T-cell recruitment and activation. killing of GPRC5-expressing MM cells through T cell recruitment and activation.Talquetamab (JNJ-64407564) has antitumor activity. | ||
| M29016 | BPN-15606 | Gamma-secretase/Beta-secretase |
| BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 has acceptable PK/PD properties, including bioavailability, half-life, and clearance. | ||
| M30801 | KPT-6566 | Others |
| KPT-6566 is a selective and covalent prolyl isomerase PIN1 inhibitor, covalently binds to the catalytic site of PIN1, selectively inhibits and degrades PIN1. KPT-6566 shows an IC50 value of 640 nM and a Ki value of 625.2 nM for PIN1 PPIase domain. KPT-6566 can be used for the research of cancer. | ||
| M31065 | BPN-15606 besylate | Gamma-secretase/Beta-secretase |
| BPN-15606 besylate is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 besylate lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 besylate has acceptable PK/PD properties, including bioavailability, half-life, and clearance. | ||
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