About 8 results found for searched term "5-fluorouracil" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2289 | 5-fluorouracil | DNA/RNA Synthesis |
| 5-FU, Carac, Efudex; Adrucil | ||
| 5-fluorouracil (5-FU) is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. | ||
| M39541 | 5-Chlorouracil (fluorouracil impurity) | Others |
| 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M2247 | Carmofur | DNA/RNA Synthesis |
| HCFU | ||
| Carmofur is a pyrimidine analog that is a prodrug of 5-fluorouracil (5-FU), which inhibits DNA Synthesis and has better antiproliferative activity than 5-FU. Carmofur is an inhibitor of Acidic Ceramidase (ASAH1) and a potential lead compound for non-cancer diseases such as Krabbe disease, acute lung injury (ALI), Parkinson's disease (PD), dementia, etc. Carmofur also has antifungal and antimicrobial properties. | ||
| M5648 | Floxuridine | DNA/RNA Synthesis |
| Deoxyfluorouridine; FDUR; NSC 27640 | ||
| Floxuridine (5-fluorouracil 2'-deoxyriboside) is a pyrimidine analogue that is also an antitumor metabolite of oncology. Floxuridine inhibits the Poly(ADP-Ribose) polymerase and induces DNA damage in vitro by activating ATM and ATR checkpoint signaling pathways. Floxuridine is an effective inhibitor of Staphylococcus aureus infection and can induce apoptosis. Floxuridine is resistant to HSV and CMV viruses. | ||
| M16195 | Thymine | Alkaloids |
| Thymine is one of the four bases of DNA that can be used as a target for 5-fluorouracil (5-FU) in animal cancer models with a Km value of 2.3 μM. | ||
| M19166 | Martynoside | Others |
| Martynoside protects ex vivo bone marrow cells from 5-fluorouracil (5-FU)-induced cell death and inflammation response by down-regulating the TNF signaling pathway. Martynoside is a potent antiestrogen in MCF-7 cells, increasing IGFBP3 levels | ||
| M21143 | 5-Fluorouridine | DNA/RNA Synthesis |
| 5-Fluorouridine is a metabolite of 5-fluorouracil, a potent inhibitor of nuclease autocleavage. 5-Fluorouridine binds to total and poly A RNA and has antiproliferative activity. 5-Fluorouridine induces apoptosis (cell death). | ||
| M40893 | Ethyl chloroacetate | Plant growth regulators |
| Ethyl chloroacetate is used as a raw material for the preparation of the insecticide azoxystrobin and the herbicide ethyl chlormequat, as well as for the synthesis of 5-fluorouracil (5-FU). | ||
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